Piper methysticum extract
Piper methysticum extract extract is obtained from Piper methysticum, Piperaceae, and used to relax the body and mood, restore physical strength, and reduce pain. Piper methysticum extract is a more popular treatment of anxiety herb and is considered to be a non-addictive non-toxic herb. It has anti-anxiety, anti-fungal, anti-irritation, anti-inflammatory, soothing, sedative and other effects. It can effectively reduce the stimulation of skin neurons and inhibit the activation of NF-kB signal.
For research use only. We do not sell to patients.
- CAS No.: 84696-40-2
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Chemical Information
-
CAS No. 84696-40-2
-
SMILES
[Piper methysticum extract ]
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Research Protocol for Inflammation-related Diseases
The NLRP3 inflammasome is a cytosolic innate immune signaling platform that integrates priming signals and danger-signal activation to promote caspase-1 activation, maturation of IL-1β and IL-18, and gasdermin D-mediated pyroptotic cell death. The core experimental logic is to determine whether inflammatory disease phenotypes are driven by increased NLRP3 expression, ASC-containing inflammasome assembly, caspase-1 cleavage, GSDMD cleavage, and extracellular release of IL-1β/IL-18 rather than by nonspecific cell injury alone. The pathway is strongly linked to inflammation-related disease phenotypes because monosodium urate crystals activate NALP3/NLRP3 inflammasome signaling in gout-like crystal inflammation, cholesterol crystals activate NLRP3 inflammasomes in atherogenesis models, and DSS-induced intestinal inflammation has been reported to involve NLRP3 inflammasome activity. However, experimental colitis studies also show context-dependent protective effects of NLRP3 inflammasome co
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)