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Cat. No.: HY-P11113

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PFVYLI

PFVYLI is a hydrophobic penetrating peptide that can be used to modify doxorubicin-loaded stealth persistent liposomes (PFV-ssls-dox) for breast cancer research.

For research use only. We do not sell to patients.

CAS No.: 1252672-28-8
Formula: C₄₀H₅₈N₆O₈
Molecular Weight:750.92

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

PFVYLI Chemical Structure

CAS No.: 1252672-28-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

PFVYLI is a hydrophobic penetrating peptide that can be used to modify doxorubicin-loaded stealth persistent liposomes (PFV-ssls-dox) for breast cancer research^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
MT2	IC₅₀	>100 μM Compound: PI6	Antiviral activity against Human immunodeficiency virus 1 3B infected in human MT2 cells assessed as inhibition of viral replication after 4 days by ELISA Antiviral activity against Human immunodeficiency virus 1 3B infected in human MT2 cells assessed as inhibition of viral replication after 4 days by ELISA	[PMID: 22406118]

Chemical Information

CAS No. 1252672-28-8
Molecular Weight 750.92
Formula C₄₀H₅₈N₆O₈
Sequence

Pro-Phe-Val-Tyr-Leu-Ile
Sequence Shortening

PFVYLI
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Cai D, et al. Hydrophobic penetrating peptide PFVYLI-modified stealth liposomes for doxorubicin delivery in breast cancer therapy. Biomaterials. 2014 Feb;35(7):2283-94. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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