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Cat. No.: HY-172785

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PI3K-IN-57

PI3K-IN-57 (Compound 4a) is a PI3K inhibitor that has a strong inhibitory effect on the proliferation of HeLa tumor heterotopic xenografts in vivo. PI3K-IN-57 is promising for research of anti-cancer agent.

For research use only. We do not sell to patients.

Formula: C₂₆H₂₈N₄O₄
Molecular Weight:460.52

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

PI3K-IN-57 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All PI3K Isoforms :

Chemical Information

Molecular Weight 460.52
Formula C₂₆H₂₈N₄O₄
SMILES

CCCCN(C1=NC=NC(OC2=CC(O)=C3C(C=C(OC3=C2)C4=CC=CC=C4)=O)=N1)CCCC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Xue XY, et al. Design, synthesis, bioactivity, X-ray crystallography, and molecular docking studies of chrysin-1,3,5-triazine derivatives as anticancer agents. Bioorg Chem. 2025 Apr 16;161:108486. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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