PI3Kδ-IN-22
PI3Kδ-IN-22 (Compound 26) is a selective inhibitor for PI3Kδ with pKi of 9.3. PI3Kδ-IN-22 inhibits PI3Kδ-AKT signaling pathway in THP-1 cells, with pIC50 of 9.4. PI3Kδ-IN-22 exhibits good pharmacokinetic characters in rats.
For research use only. We do not sell to patients.
- Formula: C27H35FN8O4S
- Molecular Weight:586.68
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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PI3Kδ 9.3 (pKi) |
PI3Kβ 7.7 (pKi) |
PI3Kα 7.3 (pKi) |
PI3Kγ 6.5 (pKi) |
Chemical Information
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Molecular Weight 586.68
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Formula C27H35FN8O4S
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SMILES
O=C1N(C(C)(C)C)N=CC([C@@H](N2N=C(C3=CC(F)=CC(O)=C3)C4=C2N=CN=C4N)C)=C1SCCN(CCO)CCO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PI3Kδ-IN-22 Related Classifications
HY-162647 Related Classifications
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