PI5P4Ks-IN-2
Based on 1 Customer Validation
PI5P4Ks-IN-2 is a inhibitor of phosphatidylinositol 5-phosphate 4-kinase γ (PI5P4Kγ). PI5P4Ks-IN-2 targets to PI5P4K isoforms with pIC50 values of <4.3 (PI5P4Kα), <4.6 (PI5P4Kβ), 6.2 (PI5P4Kγ), 0.32 (PI5P4Kγ+), respectively.
For research use only. We do not sell to patients.
- Purity : 99.78%
- CAS No.: 2766854-03-7
- Formula: C22H23N5
- Molecular Weight:357.45
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
PI5P4K[1]
In Vitro
Chemical Information
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CAS No. 2766854-03-7
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Appearance Solid
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Molecular Weight 357.45
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Formula C22H23N5
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Color White to off-white
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SMILES
CN1C=CC2=C1C(NCC3=NC=CC=C3)=NC(C4=CC=CC=C4C(C)C)=N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 125 mg/mL (349.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7976 mL | 13.9880 mL | 27.9759 mL | 69.9398 mL |
| 5 mM | 0.5595 mL | 2.7976 mL | 5.5952 mL | 13.9880 mL | |
| 10 mM | 0.2798 mL | 1.3988 mL | 2.7976 mL | 6.9940 mL | |
| 15 mM | 0.1865 mL | 0.9325 mL | 1.8651 mL | 4.6627 mL | |
| 20 mM | 0.1399 mL | 0.6994 mL | 1.3988 mL | 3.4970 mL | |
| 25 mM | 0.1119 mL | 0.5595 mL | 1.1190 mL | 2.7976 mL | |
| 30 mM | 0.0933 mL | 0.4663 mL | 0.9325 mL | 2.3313 mL | |
| 40 mM | 0.0699 mL | 0.3497 mL | 0.6994 mL | 1.7485 mL | |
| 50 mM | 0.0560 mL | 0.2798 mL | 0.5595 mL | 1.3988 mL | |
| 60 mM | 0.0466 mL | 0.2331 mL | 0.4663 mL | 1.1657 mL | |
| 80 mM | 0.0350 mL | 0.1748 mL | 0.3497 mL | 0.8742 mL | |
| 100 mM | 0.0280 mL | 0.1399 mL | 0.2798 mL | 0.6994 mL |
PI5P4Ks-IN-2 Related Classifications
HY-153526 Related Classifications
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