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Cat. No.: HY-153529

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PI5P4Ks-IN-3

PI5P4Ks-IN-3 (compound 30) is a covalent inhibitor of PI5P4K with IC₅₀s of 1.34 μM (PI5P4Kα)，and 9.9 μM (PI5P4Kβ)，respectively. PI5P4Ks-IN-3 shows weak cellular activity.

For research use only. We do not sell to patients.

CAS No.: 2471969-07-8
Formula: C₃₂H₃₁N₇O₂
Molecular Weight:545.63

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

PI5P4Ks-IN-3 Chemical Structure

CAS No.: 2471969-07-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

PI5P4Ks-IN-3 (compound 30) is a covalent inhibitor of PI5P4K with IC₅₀s of 1.34 μM (PI5P4Kα)，and 9.9 μM (PI5P4Kβ)，respectively. PI5P4Ks-IN-3 shows weak cellular activity^[1].

IC₅₀ & Target

IC50: 1.34 μM (PI5P4Kα), and 9.9 μM (PI5P4Kβ)^[1]

Chemical Information

CAS No. 2471969-07-8
Molecular Weight 545.63
Formula C₃₂H₃₁N₇O₂
SMILES

CC(C=C1)=CC=C1N2C3=NC=NC(NC4=CC(NC(C5=CC=C(C=C5)NC(/C=C/CN(C)C)=O)=O)=CC=C4)=C3C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Manz TD, et al. Structure-Activity Relationship Study of Covalent Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors. ACS Med Chem Lett. 2019 Nov 3;11(3):346-352. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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