Polyvinyl alcohol (Mw 146000-186000, 87-89% hydrolyzed)
Based on 3 publication(s) in Google Scholar
Polyvinyl alcohol (Mw 146000-186000, 87-89% hydrolyzed) is a polyvinyl alcohol with a molecular weight of 146000-186000 and hydrolytic properties. Polyvinyl alcohol (Mw 146000-186000, 87-89% hydrolyzed) is the hydrolysis and removal of acetate groups after the polymerization of ethylene acetate. And polyvinyl alcohol is obtained. Polyvinyl alcohol with different degrees of hydrolysis can be used to self-crosslink to form cryogel, which can be used as biological excipient. Polyvinyl alcohol can be used in tissue engineering by electrospinning. Polyvinyl alcohol can achieve high cellular density, infiltration, and uniform distribution, facilitating functional connections between cells. Polyvinyl alcohol can improve cell vitality through in vitro cultivation. Polyvinyl alcohol demonstrates promising inhibition of ostersarcoma cancer cells with Doxorubicin (HY-15142A).
For research use only. We do not sell to patients.
- Assay : 88.10%
- CAS No.: 9002-89-5
- Formula: (C2H4O)n
- Molecular Weight:146000-186000 (Approximately)
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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HY-Y0850E
Polyvinyl alcohol (Mw 30000-70000, 87-90% hydrolyzed)Dressing Meterial -
HY-Y0850
Polyvinyl alcohol (Mw 146000-186000, 99+% hydrolyzed)Biochemical reagents -
HY-Y0850J
Polyvinyl alcohol (Mw 13000-23000, 87-89% hydrolyzed)Polyvinyl Alcohol -
HY-Y0850U4
PVA (Mw 145000, 99+% hydrolyzed, ~3300 polymerization)Polyvinyl Alcohol -
HY-Y0850U
PVA (Mw 31000, 87-89% hydrolyzed, ~630 polymerization)Polymer -
HY-Y0850K
Polyvinyl alcohol (Mw 31000-50000, 98-99% hydrolyzed)Biochemical Reagent -
HY-Y0850O
Polyvinyl alcohol (Mw 31000-50000, 87-89% hydrolyzed)Emulsification Stabilizer -
HY-Y0850H
Polyvinyl alcohol (Mw 89000-98000, 99+% hydrolyzed)Biochemical Reagent -
HY-Y0850I
Polyvinyl alcohol (Mw 9000-10000, 80% hydrolyzed)Biochemical Reagent -
HY-Y0850U6
PVA (Mw 205000)Polyvinyl Alcohol -
HY-Y0850N
Polyvinyl alcohol (Mw 13000-23000, 98% hydrolyzed)Biochemical Reagent -
HY-Y0850U3
PVA (Mw 125000, 98-99% hydrolyzed, ~2800 polymerization)Wound Dressing
Publications Citing Use of MedChemExpress (MCE) Polyvinyl alcohol (Mw 146000-186000, 87-89% hydrolyzed)
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Biological Activity
Description
In Vitro
Polyvinyl alcohol during in vitro cultivation enables adherent growth on the membrane post PVA degradation with cells still enveloped by PVA after 24 h[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 9002-89-5
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Appearance Solid
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Molecular Weight 146000-186000 (Approximately)
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Formula (C2H4O)n
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Color White to off-white
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SMILES
CCC(O)C.[n]
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Synonyms
PVA (Mw 146000-186000, 87-89% hydrolyzed); Poly(Ethenol) (Mw 146000-186000, 87-89% hydrolyzed)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Publications (3)
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Journal Impact Factor
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Most Recent
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Nanoscale Adv
Dexamethasone-loaded lipid-polymeric nanoparticles to improve therapy for cisplatin-induced sensorineural hearing loss. [Abstract]2025 Nov 21. PMID: 41278499 -
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Solvent & Solubility
In Vitro:
H2O : 4 mg/mL (Need ultrasonic)
Protocols
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3D Hydrogel Synthetic Scaffold Culture
3D hydrogel synthetic scaffold culture embeds cells, spheroids, organoids, or tissue fragments inside a hydrated crosslinked polymer network so that cells receive matrix and cell-cell cues in three dimensions rather than from a flat plastic surface. A literature-supported model protocol is PEG-4MAL hydrogel culture, in which four-arm maleimide-terminated PEG is functionalized with cysteine-containing adhesive peptides such as RGD and crosslinked with protease-degradable peptides such as GPQ-W; this creates a defined, modular scaffold that supports human organoid generation and culture. The readouts are scaffold-supported growth, morphology, lumen formation, budding, viability, proliferation, lineage-marker expression, and matrix-dependent expansion or differentiation; reported assays include transmitted-light imaging, immunofluorescence, in situ hybridization, qRT-PCR, and rheological characterization.
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Elsherbiny DA, et al. Self-crosslinked polyvinyl alcohol/cellulose nanofibril cryogels loaded with synthesized aminophosphonates as antimicrobial wound dressings. J Mater Chem B. 2023 Aug 2;11(30):7144-7159. [Content Brief]
[2]. Türkoğlu, G. C., et al., (2024). PVA-Based Electrospun Materials-A Promising Route to Designing Nanofiber Mats with Desired Morphological Shape-A Review. International journal of molecular sciences, 25(3), 1668. [Content Brief]
[3]. DeMerlis CC, et al. Review of the oral toxicity of polyvinyl alcohol (PVA). Food Chem Toxicol. 2003 Mar;41(3):319-26. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Polyvinyl alcohol (Mw 146000-186000, 87-89% hydrolyzed) Related Classifications
HY-Y0850P Related Classifications
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