Pomalidomide-C6-O-C5-O-C4-COOH

Cat. No.: HY-148362 Purity: 98.55%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Pomalidomide-C6-O-C5-O-C4-COOH is a E3 ligase ligand-linker conjugate comprising a Pomalidomide (HY-10984)-based cereblon ligand and linker. Pomalidomide-C6-O-C5-O-C4-COOH can be used for the synthesis of PROTACs.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Pomalidomide-C6-O-C5-O-C4-COOH 화학구조

CAS No. : 2375774-54-0

사이즈	재고	수량
Oil + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	해외재고보유	Estimated Time of Arrival: December 31
Oil
10 mg	해외재고보유	Estimated Time of Arrival: December 31
25 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	해외재고보유	Estimated Time of Arrival: December 31
100 mg	해외재고보유	Estimated Time of Arrival: December 31
200 mg	견적 받기
500 mg	견적 받기

or 대량구매 문의

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

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•Related Small Molecules:

•Related Proteins:

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von Hippel-Lindau (VHL) MDM2 Cereblon cIAP1 Aryl Hydrocarbon Receptor TRIM21

Biological Activity
순도&문서
References
고객리뷰

제품 설명

분자량

559.65

화학식

C₂₉H₄₁N₃O₈

CAS No.

2375774-54-0

Appearance

Oil

Color

Light yellow to yellow

SMILES

O=C(O)CCCCOCCCCCOCCCCCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O

선적

Room temperature in continental US; may vary elsewhere.

보관

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도

In Vitro:

DMSO : 100 mg/mL (178.68 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.7868 mL	8.9342 mL	17.8683 mL
5 mM	0.3574 mL	1.7868 mL	3.5737 mL
10 mM	0.1787 mL	0.8934 mL	1.7868 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

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(per animal)

μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

순도&문서

Purity: 98.55%

Select Batch:

Data Sheet (264 KB) SDS (252 KB)

COA (242 KB) HNMR (246 KB) LCMS (96 KB)

Handling Instructions (2659 KB)

References

[1]. Steinebach C , et al. PROTAC-mediated crosstalk between E3 ligases. Chem Commun (Camb). 2019 Feb 5;55(12):1821-1824. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.7868 mL	8.9342 mL	17.8683 mL	44.6708 mL
	5 mM	0.3574 mL	1.7868 mL	3.5737 mL	8.9342 mL
	10 mM	0.1787 mL	0.8934 mL	1.7868 mL	4.4671 mL
	15 mM	0.1191 mL	0.5956 mL	1.1912 mL	2.9781 mL
	20 mM	0.0893 mL	0.4467 mL	0.8934 mL	2.2335 mL
	25 mM	0.0715 mL	0.3574 mL	0.7147 mL	1.7868 mL
	30 mM	0.0596 mL	0.2978 mL	0.5956 mL	1.4890 mL
	40 mM	0.0447 mL	0.2234 mL	0.4467 mL	1.1168 mL
	50 mM	0.0357 mL	0.1787 mL	0.3574 mL	0.8934 mL
	60 mM	0.0298 mL	0.1489 mL	0.2978 mL	0.7445 mL
	80 mM	0.0223 mL	0.1117 mL	0.2234 mL	0.5584 mL
	100 mM	0.0179 mL	0.0893 mL	0.1787 mL	0.4467 mL