1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Potassium 2-hydroxy-2-methylsuccinate

Potassium 2-hydroxy-2-methylsuccinate 

Cat. No.: HY-23195 Purity: ≥98.0%
COA Handling Instructions

Potassium 2-hydroxy-2-methylsuccinate is an endogenous metabolite.

For research use only. We do not sell to patients.

Potassium 2-hydroxy-2-methylsuccinate Chemical Structure

Potassium 2-hydroxy-2-methylsuccinate Chemical Structure

CAS No. : 1030365-02-6

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50 mg USD 80 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Potassium 2-hydroxy-2-methylsuccinate is an endogenous metabolite.

Molecular Weight

224.29

Formula

C5H6K2O5

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C([O-])C(C)(O)CC([O-])=O.[K+].[K+]

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (1114.63 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.4585 mL 22.2926 mL 44.5851 mL
5 mM 0.8917 mL 4.4585 mL 8.9170 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.4585 mL 22.2926 mL 44.5851 mL 111.4628 mL
5 mM 0.8917 mL 4.4585 mL 8.9170 mL 22.2926 mL
10 mM 0.4459 mL 2.2293 mL 4.4585 mL 11.1463 mL
15 mM 0.2972 mL 1.4862 mL 2.9723 mL 7.4309 mL
20 mM 0.2229 mL 1.1146 mL 2.2293 mL 5.5731 mL
25 mM 0.1783 mL 0.8917 mL 1.7834 mL 4.4585 mL
30 mM 0.1486 mL 0.7431 mL 1.4862 mL 3.7154 mL
40 mM 0.1115 mL 0.5573 mL 1.1146 mL 2.7866 mL
50 mM 0.0892 mL 0.4459 mL 0.8917 mL 2.2293 mL
60 mM 0.0743 mL 0.3715 mL 0.7431 mL 1.8577 mL
80 mM 0.0557 mL 0.2787 mL 0.5573 mL 1.3933 mL
100 mM 0.0446 mL 0.2229 mL 0.4459 mL 1.1146 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Potassium 2-hydroxy-2-methylsuccinate Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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