PRL-3 Inhibitor I
Based on 1 publication(s) in Google Scholar
PRL-3 Inhibitor I is a potent PRL-3 inhibitor with an IC50 of 0.9 μM. PRL-3 Inhibitor I shows a reduced invasion in cell-based assay.
For research use only. We do not sell to patients.
- Purity: 98.11%
- CAS No.: 893449-38-2
- Formula: C17H11Br2NO2S2
- Molecular Weight:485.21
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) PRL-3 Inhibitor I
More
Biological Activity
IC50: 0.9 μM (PRL-3)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| DLD-1 | IC50 |
7 μM
Compound: BR-1
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Antimigratory activity against human DLD1 cells overexpressing PRL3 by crystal violet staining-based light microscopic analysis
Antimigratory activity against human DLD1 cells overexpressing PRL3 by crystal violet staining-based light microscopic analysis
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[PMID: 23726031] |
PRL-3 Inhibitor I (compound 5e) reduces the invasion of mouse melanoma B16F10 cells in a cell-based assay[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 893449-38-2
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Appearance Solid
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Molecular Weight 485.21
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Formula C17H11Br2NO2S2
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Color Light yellow to green yellow
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SMILES
O=C1NC(S/C1=C/C2=CC(Br)=CC=C2OCC3=CC=CC=C3Br)=S
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
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Lung Cancer
NOTCH and PTP4A3 alterations emerge as novel predictive biomarkers and potential therapeutic targets in pleural mesothelioma. [Abstract]2024 Nov 7:198:108024. PMID: 39547104
Solvent & Solubility
DMSO : 41.67 mg/mL (85.88 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : < 0.1 mg/mL (insoluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (538 KB)
- English - EN (538 KB)
- Français - FR (538 KB)
- Deutsch - DE (538 KB)
- Norwegian - NO (538 KB)
- Español - ES (538 KB)
- Swedish - SV (538 KB)
- Italian - IT (538 KB)
- Korean - KR (538 KB)
- Portuguese - PT (538 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0610 mL | 10.3048 mL | 20.6096 mL | 51.5241 mL |
| 5 mM | 0.4122 mL | 2.0610 mL | 4.1219 mL | 10.3048 mL | |
| 10 mM | 0.2061 mL | 1.0305 mL | 2.0610 mL | 5.1524 mL | |
| 15 mM | 0.1374 mL | 0.6870 mL | 1.3740 mL | 3.4349 mL | |
| 20 mM | 0.1030 mL | 0.5152 mL | 1.0305 mL | 2.5762 mL | |
| 25 mM | 0.0824 mL | 0.4122 mL | 0.8244 mL | 2.0610 mL | |
| 30 mM | 0.0687 mL | 0.3435 mL | 0.6870 mL | 1.7175 mL | |
| 40 mM | 0.0515 mL | 0.2576 mL | 0.5152 mL | 1.2881 mL | |
| 50 mM | 0.0412 mL | 0.2061 mL | 0.4122 mL | 1.0305 mL | |
| 60 mM | 0.0343 mL | 0.1717 mL | 0.3435 mL | 0.8587 mL | |
| 80 mM | 0.0258 mL | 0.1288 mL | 0.2576 mL | 0.6441 mL |
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