PROTAC BRD4-DCAF1 degrader-1
PROTAC BRD4-DCAF1 degrader-1 (I-907) is a BRD4-DCAF1 PROTAC degrader, DC50 is 10~100 nM. .
(Pink: BRD4 ligand (HY-78695); Blue: DCAF1 ligand (HY-169152); Black: linker (HY-126976)).
For research use only. We do not sell to patients.
- CAS No.: 3036944-87-0
- Formula: C60H64Cl2F2N8O9S
- Molecular Weight:1182.17
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All PROTACs Isoforms
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Biological Activity
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BRD4 |
PROTAC is composed of three parts: a ligand that specifically binds to the target protein, an E3 ubiquitin ligase that recruits the ligand, and a chemical linker that connects the two. It induces the ubiquitination of the target protein by forming a ternary complex and then degrades it by the proteasome.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3036944-87-0
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Molecular Weight 1182.17
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Formula C60H64Cl2F2N8O9S
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SMILES
CC1=C(C)SC2=C1C(C3=CC=C(C=C3)Cl)=N[C@@H](CC(NCCOCCOCCOCCOCCOCCCC4=CC=C(C=C4)C(C5=C(C6=C(C(F)=CC=C6F)C)C(C(N[C@H](C7=CC(Cl)=CC=C7)CC(N)=O)=O)=CN5)=O)=O)C8=NN=C(C)N28
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC BRD4-DCAF1 degrader-1 Related Classifications
HY-169151 Related Classifications
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