2. Recombinant Proteins
  3. Cytokines and Growth Factors
  4. TNF Superfamily
  5. TNF Receptor Superfamily
  6. Death Receptor 4

Death Receptor 4

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Cat. No. Product Name / Synonyms Species Source
  • HY-P78219
    TRAIL R1/TNFRSF10A Protein, Human (Biotinylated, HEK293, His-Avi)

    DR4; CD261; TNFRSF10A; TRAIL-R; APO2; TRAIL R1; MGC9365

    		Human HEK293
    TRAIL R1/TNFRSF10A protein is a receptor for TNFSF10/TRAIL, which recruits caspase-8 through FADD to initiate cell apoptosis and form a death-inducing signaling complex (DISC). It activates NF-kappa-B and interacts with TRADD and RIPK1 in the monomeric state. TRAIL R1/TNFRSF10A Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived TRAIL R1/TNFRSF10A protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of TRAIL R1/TNFRSF10A Protein, Human (Biotinylated, HEK293, His-Avi) is 206 a.a., with molecular weight of 25-30 kDa.
  • HY-P72440
    TRAIL R1/TNFRSF10A Protein, Human (216a.a, HEK293, His)

    Tumor necrosis factor receptor superfamily member 10A; TRAIL-R1; CD261; TNFRSF10A; APO2; DR4

    		Human HEK293
    TRAIL R1/TNFRSF10A protein is a receptor for TNFSF10/TRAIL, which recruits caspase-8 through FADD to initiate cell apoptosis and form a death-inducing signaling complex (DISC). It activates NF-kappa-B and interacts with TRADD and RIPK1 in the monomeric state. TRAIL R1/TNFRSF10A Protein, Human (216a.a, HEK293, His) is the recombinant human-derived TRAIL R1/TNFRSF10A protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TRAIL R1/TNFRSF10A Protein, Human (216a.a, HEK293, His) is 216 a.a., with molecular weight of 19-30 kDa.
  • HY-P78529
    TRAIL R1/TNFRSF10A Protein, Human (HEK293, His-Avi)

    DR4; CD261; TNFRSF10A; TRAIL-R; APO2; TRAIL R1; MGC9365

    		Human HEK293
    TRAIL R1/TNFRSF10A Protein, a receptor for TNFSF10/TRAIL, initiates apoptosis by recruiting caspase-8 via FADD, forming the death-inducing signaling complex (DISC). It activates NF-kappa-B and interacts with TRADD and RIPK1 in its monomeric state. TRAIL R1/TNFRSF10A forms homooligomers and heterooligomers with TNFRSF10B, interacting with the TNFSF10 homotrimer. It also interacts with ARAP1 and ZDHHC3, highlighting its role in complex signaling networks. In the absence of stimulation, it interacts with BIRC2, DDX3X, and GSK3B, and stimulation enhances these interactions, accompanied by cleavage of DDX3X and BIRC2, emphasizing its multifaceted role in apoptotic and signaling pathways. TRAIL R1/TNFRSF10A Protein, Human (HEK293, His-Avi) is the recombinant human-derived TRAIL R1/TNFRSF10A protein, expressed by HEK293, with C-Avi, C-His labeled tag. The total length of TRAIL R1/TNFRSF10A Protein, Human (HEK293, His-Avi) is 206 a.a., with molecular weight of 25-30 kDa.
  • HY-P74500
    TRAIL R1/TNFRSF10A Protein, Human (HEK293, hFc)

    Tumor necrosis factor receptor superfamily member 10A; TRAIL-R1; CD261; APO2; DR4

    		Human HEK293
    TRAIL R1/TNFRSF10A protein is a receptor for TNFSF10/TRAIL, which recruits caspase-8 through FADD to initiate cell apoptosis and form a death-inducing signaling complex (DISC). It activates NF-kappa-B and interacts with TRADD and RIPK1 in the monomeric state. TRAIL R1/TNFRSF10A Protein, Human (HEK293, hFc) is the recombinant human-derived TRAIL R1/TNFRSF10A protein, expressed by HEK293 , with C-hFc labeled tag. The total length of TRAIL R1/TNFRSF10A Protein, Human (HEK293, hFc) is 216 a.a., with molecular weight of ~47 kDa.
Cat. No. Product Name Effect Purity