Prussian blue insoluble
Based on 1 Customer Validation
Prussian blue soluble is a good adsorbent to be used as antidotes for poisoning with cesium or thallium ions. Prussian blue soluble has anticancerous and antibacterial properties. Prussian blue soluble can be used as a contrast agent in photoacoustic and magnetic resonance imaging (MRI).
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- No. CAS: 14038-43-8
- Fòrmula: Fe4[Fe(CN)6]3
- Peso molecular:859.23
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Actividad biológica
Descripciòn
In Vitro
Prussian blue insoluble (Iron(III) ferrocyanide) (0.1-3.0μg/mL; 24 hours; HUVECs) has photo-thermal effect and inhibits cell viabilities[1]. Prussian blue insoluble (Iron(III) ferrocyanide) (0.07 mM; 0-24 hours) act as a metabolic indicator, being reduced by bacterial metabolism, producing a visible color change from blue to colorless[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HUVECs
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Concentration:24 hours
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Incubation Time:0.1, 0.2, 0.5, 1.0, 2.0 and 3.0 μg/mL
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Result:Decreased the cell viabilities as the time of NIR laser irradiation
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Rats[3]
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Dosage:3 g/day
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Administration:Oral administration; 8 days
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Result:Increased excretion of cesium-134.
Chemical Information
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No. CAS 14038-43-8
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Appearance Solid
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Peso molecular 859.23
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Fòrmula Fe4[Fe(CN)6]3
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Color Blue to dark blue
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SMILES
[Fe][Fe][Fe][Fe].N#C[Fe](C#N)(C#N)(C#N)(C#N)C#N.N#C[Fe](C#N)(C#N)(C#N)(C#N)C#N.N#C[Fe](C#N)(C#N)(C#N)(C#N)C#N
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Synonyms
Iron(III) ferrocyanide; Milori blue
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Chen HJ, et, al. Facile synthesis of Prussian blue nanoparticles as pH-responsive drug carriers for combined photothermal-chemo treatment of cancer. RCS advances. 2016 Oct 9; 7:248-255. [Content Brief]
[2]. Ferrer-Vilanova A, et, al. Electrochromogenic Detection of Live Bacteria Using Soluble and Insoluble Prussian Blue. ACS Omega. 2021 Nov 11;6(46):30989-30997. [Content Brief]
[3]. Thompson DF, et, al. Soluble or insoluble prussian blue for radiocesium and thallium poisoning? Ann Pharmacother. 2004 Sep;38(9):1509-14. [Content Brief]
[4]. Busquets MA, et, al. Prussian blue nanoparticles: synthesis, surface modification, and biomedical applications. Drug Discov Today. 2020 Aug;25(8):1431-1443. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Prussian blue insoluble Related Classifications
HY-106594A Related Classifications
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