Two bioactive pentacyclic triterpene esters from the root bark of Hibiscus syriacus

  • J Nat Prod. 1999 May;62(5):764-6. doi: 10.1021/np9804637.
B S Yun  1 ,  I J Ryoo ,  I K Lee ,  K H Park ,  D H Choung ,  K H Han ,  I D Yoo
Affiliations
  • 1. Korea Research Institute of Bioscience and Biotechnology, P.O. Box 115, Yusong, Taejon 305-600, Korea.
PMID: 10346965 DOI: 10.1021/np9804637
Abstract

Two new triterpene caffeates have been isolated from the root bark of Hibiscus syriacus. Their structures were established through various spectral studies as 3beta,23,28-trihydroxy-12-oleanene 23-caffeate (1) and 3beta,23,28-trihydroxy-12-oleanene 3beta-caffeate (2). Compounds 1 and 2 showed lipid peroxidation inhibitory activity and significant cytotoxicity against a panel of human Cancer cell lines.