Gilvusmycin, a new antitumor antibiotic related to CC-1065

  • J Antibiot (Tokyo). 1999 Mar;52(3):263-8. doi: 10.7164/antibiotics.52.263.
Y Tokoro  1 ,  T Isoe ,  K Shindo
Affiliations
  • 1. Pharmaceutical Research Laboratory, Kirin Brewery Co., Ltd., Gunma, Japan.
PMID: 10348041 DOI: 10.7164/antibiotics.52.263
Abstract

A new antitumor Antibiotic gilvusmycin was isolated from the culture broth of Streptomyces sp. QM16. The structure of gilvusmycin was related to CC-1065 and determined by NMR spectral analysis. Gilvusmycin exhibited antitumor activity against murine leukemia P388 in vivo.

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