Acyclic structural variants of growth hormone secretagogue L-692,429

  • Bioorg Med Chem Lett. 1999 Nov 15;9(22):3237-42. doi: 10.1016/s0960-894x(99)00568-5.
P Lin  1 ,  J M Pisano ,  W R Schoen ,  K Cheng ,  W W Chan ,  B S Butler ,  R G Smith ,  M H Fisher ,  M J Wyvratt
Affiliations
  • 1. Department of Medicinal Chemistry, Merck Research Laboratories, Rahway, NJ 07065, USA.
PMID: 10576695 DOI: 10.1016/s0960-894x(99)00568-5
Abstract

Systematic investigation of acyclic analogs of L-692,429, the prototype benzolactam growth hormone secretagogue, has helped to further define the structural requirements for the release of growth hormone from rat pituitary cells for this class of secretagogues.