A new lanostane-type triterpene from the fruiting bodies of Ganoderma lucidum

  • J Asian Nat Prod Res. 2002 Jun;4(2):129-34. doi: 10.1080/10286020290027416.
Jun Luo  1 ,  Yu-Ying Zhao ,  Zhi-Bin Li
Affiliations
  • 1. Department of Pharmacology, School of Basic Medical Science, Peking University, Beijing, China.
PMID: 12067158 DOI: 10.1080/10286020290027416
Abstract

A new lanostane-type triterpene, named ganoderic acid LM2 (5), was isolated from the fruiting bodies of Ganoderma lucidum. Its structure was characterized as (23S) 7beta, -dihydroxy-3, 11, 15-trioxo-5alpha-lanosta-8, 24-dien-26-oic acid by 1D- and 2D-NMR spectra. In addition, a known triterpene, ganoderic acid epsilon (4), was obtained. Both of them exhibited potent enhancement of ConA-induced mice splenocytes proliferation in vitro.

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