A convenient gram-scale synthesis of uridine diphospho(13C6)glucose

  • Carbohydr Res. 2006 Jul 24;341(10):1743-7. doi: 10.1016/j.carres.2006.02.033.
Zoran Dinev  1 ,  Ahmad Z Wardak ,  Robert T C Brownlee ,  Spencer J Williams
Affiliations
  • 1. School of Chemistry, University of Melbourne, Parkville, Victoria 3010, Australia.
PMID: 16603138 DOI: 10.1016/j.carres.2006.02.033
Abstract

A simple gram-scale synthesis of uridine diphospho(13C6)glucose is presented from D-(13C6)glucose. The critical step uses a 1H-tetrazole-catalyzed coupling of 2,3,4,6-tetra-O-acetyl-alpha-D-glucopyranosyl-1-phosphate and UMP-morpholidate. The uridine diphospho(13C6)glucose was used in the structural identification of (1-->3)-beta-D-glucan from Lolium multiflorum.

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