Furoquinoline alkaloids from Melicope bonwickii (F.Muell.) T.Hartley

  • Nat Prod Res. 2006 Apr;20(4):355-60. doi: 10.1080/14786410500462983.
Ismiarni Komala  1 ,  Mawardi Rahmani ,  Mohd Aspollah Sukari ,  Hazar Bebe Mohd Ismail ,  Gwendoline Ee Cheng Lian ,  Asmah Rahmat
Affiliations
  • 1. Department of Chemistry, Universiti Putra Malaysia, 43400 UPM, Serdang, Malaysia.
PMID: 16644530 DOI: 10.1080/14786410500462983
Abstract

Investigation on the leaves of Melicope bonwickii (F.Muell.) T.Hartley (Rutaceae) afforded a new 7-(2'-hydroxy-3'-chloroprenyloxy)-4-methoxyfuroquinoline (1) together with the known 7-(2',3'-epoxyprenyloxy)-4-methoxyfuroquinoline (2), evellerine (3) kokusaginine (4) and an amide aurantiamide acetate (5). Compounds 1 and 2 showed significant activity against cervical cell lines (Hela).

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