5-Bromo-8-methoxy-1-methyl-beta-carboline, an alkaloid from the New Zealand marine bryozoan Pterocella vesiculosa

  • J Nat Prod. 2009 Apr;72(4):796-8. doi: 10.1021/np8007655.
Marisa Till  1 ,  Michèle R Prinsep
Affiliations
  • 1. Department of Chemistry, UniVersity of Waikato, Private Bag, Hamilton, New Zealand.
PMID: 19220033 DOI: 10.1021/np8007655
Abstract

A new alkaloid, 5-bromo-8-methoxy-1-methyl-beta-carboline (1), has been isolated from the New Zealand marine bryozoan Pterocella Vesiculosa. Structural elucidation was achieved through NMR spectroscopic and mass spectrometric analysis, and a single-crystal X-ray diffraction analysis of 1 was performed. The biological activity of 1 was assessed against P388 murine leukemia cells and three Microorganisms and compared with that of a number of related beta-carboline Alkaloids.