Synthesis and antifungal activity of some substituted phenothiazines and related compounds

  • Eur J Med Chem. 2011 Jan;46(1):101-5. doi: 10.1016/j.ejmech.2010.10.019.
Gabriela P Sarmiento  1 ,  Roxana G Vitale ,  Javier Afeltra ,  Graciela Y Moltrasio ,  Albertina G Moglioni
Affiliations
  • 1. Department of Pharmacology, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Junín 956, CABA, Argentina.
PMID: 21093111 DOI: 10.1016/j.ejmech.2010.10.019
Abstract

Several phenothiazines and related compounds were synthesized and their Antifungal activity was evaluated in vitro. The results observed for α-chloro-N-acetyl phenothiazine led us to choose this compound as a lead in the search of Antifungal agents.

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