A new alternariol glucoside from fungus Alternaria alternate cib-137

  • Nat Prod Res. 2015;29(9):848-52. doi: 10.1080/14786419.2014.990905.
Guo-Bo Xu  1 ,  Xiang Pu ,  Huan-Huan Bai ,  Xiao-Zhen Chen ,  Guo-You Li
Affiliations
  • 1. a Chengdu Institute of Biology, Chinese Academy of Sciences , Chengdu 610041 , P. R. China.
PMID: 25520187 DOI: 10.1080/14786419.2014.990905
Abstract

A new secondary metabolite, 2-O-methylalternariol 4-O-β-[4-methoxyl-glucopyranoside] (1), together with four known compounds alternariol methyl ether (2), altenuene (3), isoaltenuene (4) and 2-(2'S-hydroxypropyl)-5-methyl-7-hydroxychromone (5), was isolated from the fungus Alternaria alternate cib-137. Its structure was elucidated on the basis of spectroscopic data. Compounds 3 and 4 demonstrated moderate activity against Staphylococcus aureus.

Keywords
Alternaria alternate; glucopyranoside alternariol; metabolites; solid-state fermentation.
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