Bioactive prenylated xanthones from the stems of Cratoxylum cochinchinense

  • J Asian Nat Prod Res. 2015 May;17(5):519-31. doi: 10.1080/10286020.2015.1043902.
Ying-Hui Duan  1 ,  Yi Dai ,  Guang-Hui Wang ,  Liu-Yuan Chen ,  Hai-Feng Chen ,  De-Quan Zeng ,  Yao-Lan Li ,  Xin-Sheng Yao
Affiliations
  • 1. a Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University , Guangzhou 510632 , China.
PMID: 26043754 DOI: 10.1080/10286020.2015.1043902
Abstract

Cochinchinones M-U (1-9), together with 12 known compounds (10-21), were isolated from the stems of Cratoxylum cochinchinense (Lour.) Blume. Their structures were determined on the basis of extensive spectroscopic data analyses. In addition, their retinoid X receptor-α transcriptional activities were evaluated using an in vitro assay.

Keywords
Cratoxylum cochinchinense; Guttiferae; RXRα transcriptional activity; xanthone.
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