Patch testing in a case of eslicarbazepine and carbamazepine induced cutaneous reaction

  • Eur Ann Allergy Clin Immunol. 2018 Sep;50(5):229-231. doi: 10.23822/EurAnnACI.1764-1489.37.
E Finelli  1 P Custódio  1 O Porovska  2 S Prates  1 P Leiria-Pinto  1
Affiliations
  • 1. Immunoallergology Department, Dona Estefânia Hospital, Centro Hospitalar Lisboa Central, Lisbon, Portugal.
  • 2. Occupational Health Department, São José Hospital, Centro Hospitalar Lisboa Central, Lisbon, Portugal.
Abstract

Anticonvulsants are among the drugs most commonly involved in cutaneous adverse drug reactions (CADRs). Eslicarbazepine is a new anti-epileptic drug, chemically related to carbamazepine but with a more favorable safety profile. We report the clinical case of a woman who developed a skin rash on day 10 of eslicarbazepine with further exacerbation with eosinophilia on day 2 of carbamazepine. Epicutaneous tests were positive with eslicarbazepine.

Keywords
anticonvulsant drugs; drug allergy; epicutaneous tests; eslicarbazepine; skin rash.
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