Two new naphthalene glycosides from the seeds of Cassia obtusifolia

  • J Asian Nat Prod Res. 2019 Oct;21(10):970-976. doi: 10.1080/10286020.2018.1478816.
Xu Pang  1  2 ,  Na-Na Li  1 ,  He-Shui Yu  1 ,  Li-Ping Kang  3 ,  Hai-Yang Yu  1  2 ,  Xin-Bo Song  1 ,  Guan-Wei Fan  4 ,  Li-Feng Han  1  2
Affiliations
  • 1. Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine , Tianjin 300193 , China.
  • 2. Tianjin Key Laboratory of TCM Chemistry and Analysis, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine , Tianjin 300193 , China.
  • 3. State Key Laboratory of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences , Beijing 100700 , China.
  • 4. Central Laboratory, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine , Tianjin 300193 , China.
PMID: 29947250 DOI: 10.1080/10286020.2018.1478816
Abstract

A phytochemical study on the seeds of Cassia obtusifolia was carried out, which finally led to obtain two naphthalenes (1 and 2), two naphthopyrans (3 and 4) and twelve Anthraquinones (5-16). The structures of all compounds were established mainly by NMR and MS experiments as well as the necessary chemical evidence. Among them, 1 and 2 (obtusinaphthalensides A and B) were identified to be new naphthalene glycosides.

Keywords
Legumenosae; Semen Cassiae; naphthalene; obtusinaphthalenside.
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