Dynamic loss of hormone receptors and reshaped drug sensitivity in male breast cancer organoids: A first case report and clinical implications

  • J Transl Int Med. 2026 Apr 4;14(2):322-325. doi: 10.1515/jtim-2026-0032.
Qing Zhao  1  2  3 ,  Yunting Li  2 ,  Xiaotong Han  2  4 ,  Jingru Wang  2 ,  Xiaotong Dong  2 ,  Zhesheng Chen  5 ,  Dawei Yuan  6 ,  Yunxiang Zhang  1  2
Affiliations
  • 1. Department of Molecular Pathology, Qingdao Central Hospital, University of Health and Rehabilitation Sciences, Qingdao, Shandong Province, China.
  • 2. Center of Precision Pathologic Diagnosis, Weifang People's Hospital, Shandong Second Medical University, Weifang, Shandong Province, China.
  • 3. School of Basic Medical Sciences, Shandong University, Jinan, Shandong Province, China.
  • 4. Department of Basic Medicine, Shandong Second Medical University, Weifang, Shandong Province, China.
  • 5. Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York, USA.
  • 6. Geneis (Beijing) Co. Ltd., Beijing, China.
PMID: 42046812 DOI: 10.1515/jtim-2026-0032
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