Isolation of N-(2,6-diamino-6-hydroxymethylpimelyl)-L-alanine from Micromonospora chalcea

  • J Antibiot (Tokyo). 1981 Apr;34(4):374-80. doi: 10.7164/antibiotics.34.374.
J Shoji ,  H Hinoo ,  T Kato ,  K Nakauchi ,  S Matsuura ,  M Mayama ,  Y Yasuda ,  Y Kawamura
PMID: 7024228 DOI: 10.7164/antibiotics.34.374
Abstract

A novel dipeptide, N-(2,6-diamino-6-hydroxymethylpimelyl)-L-alanine, was isolated from the culture broth of a microorganism identified as Micromonospora chalcea. The dipeptide exhibits antimicrobial activity against Escherichia coli on a synthetic medium, and the activity is synergistically enhanced by several cell wall synthesis-inhibitors.

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