Calyxamines A and B, novel piperidine alkaloids from the Caribbean sea sponge Calyx podatypa

  • J Nat Prod. 1997 Dec;60(12):1331-3. doi: 10.1021/np970328e.
A D Rodríguez  1 ,  O M Cóbar ,  O L Padilla ,  C L Barnes
Affiliations
  • 1. Department of Chemistry, University of Puerto Rico, Río Piedras 00931-3346, USA. [email protected]
PMID: 9428165 DOI: 10.1021/np970328e
Abstract

Calyxamines A (1) and B (2) are 2,2,4,6,6-pentasubstituted Piperidine Alkaloids possessing novel carbon skeletons isolated from the marine Sponge Calyx podatypa collected in Puerto Rico. Their structures, after derivatization with trifluoroacetic acid, have been determined by a combination of X-ray and spectroscopic methods. A plausible biogenetic pathway to the calyxamines is suggested.

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