Antioxidant flavonoid glycosides from Daphniphyllum calycinum

  • J Nat Prod. 1998 May;61(5):706-8. doi: 10.1021/np9800203.
E J Gamez  1 ,  L Luyengi ,  S K Lee ,  L F Zhu ,  B N Zhou ,  H H Fong ,  J M Pezzuto ,  A D Kinghorn
Affiliations
  • 1. Program for Collaborative Research in the Pharmaceutical Sciences and Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois 60612, USA.
PMID: 9599286 DOI: 10.1021/np9800203
Abstract

A novel flavonoid diglycoside, 5,6,7,4'-tetrahydroxyflavonol 3-O-rutinoside (1), and a previously known compound, kaempferol 3-O-neohesperidoside (2), were isolated from an ethyl acetate extract of Daphniphyllum calycinum leaves that showed significant activity in a 1,1-diphenyl-2-picrylhydrazyl (DPPH) free-radical assay. The structure of 1 was elucidated by a combination of spectroscopic methods, and compounds 1 and 2 were found to be moderately active as Antioxidants in the DPPH assay.

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