QX-222 chloride (Standard)
QX-222 (chloride) (Standard) is the analytical standard of QX-222 (chloride) (HY-101362). This product is intended for research and analytical applications. QX-222 chloride, a trimethyl analogue of Lignocaine (HY-B0185), is a potent Na+ channel blocker.
For research use only. We do not sell to patients.
- CAS No.: 5369-00-6
- Formula: C13H21ClN2O
- Molecular Weight:256.77
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 5369-00-6
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Molecular Weight 256.77
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Formula C13H21ClN2O
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SMILES
O=C(NC1=C(C)C=CC=C1C)C[N+](C)(C)C.[Cl-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. A Sunami, et al. A critical residue for isoform difference in tetrodotoxin affinity is a molecular determinant of the external access path for local anesthetics in the cardiac sodium channel. Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2326-31. [Content Brief]
[2]. Qingmin Chen, et al. Differential blockade of nerve injury-induced thermal and tactile hypersensitivity by systemically administered brain-penetrating and peripherally restricted local anesthetics. J Pain. 2004 Jun;5(5):281-9. [Content Brief]
[3]. J A Flatman, et al. Reversibility of Ia EPSP investigated with intracellularly iontophoresed QX-222. J Neurophysiol. 1982 Aug;48(2):419-30. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)