2. Neuronal Signaling
  3. Monoamine Oxidase
  4. (±)-Amiflamine

(±)-Amiflamine  (Synonyms: FLA 336)

Cat. No.: HY-119885A Purity: 99.23%
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(±)-Amiflamine (FLA 336) is a potent monoamine oxidase-A (MAO-A) inhibitor with a pIC50 of 5.57.

For research use only. We do not sell to patients.

(±)-Amiflamine Chemical Structure

(±)-Amiflamine Chemical Structure

CAS No. : 77502-96-6

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50 mg USD 430 In-stock
100 mg USD 680 In-stock
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Based on 1 publication(s) in Google Scholar

(±)-Amiflamine Related Antibodies

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Description

(±)-Amiflamine (FLA 336) is a potent monoamine oxidase-A (MAO-A) inhibitor with a pIC50 of 5.57[1].

IC50 & Target[1]

MAO-A

5.57 (pIC50)

Molecular Weight

192.30

Formula

C12H20N2
CAS No.
Appearance

Oil

Color

Colorless to light yellow

SMILES

NC(CC1=CC=C(N(C)C)C=C1C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (130.01 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.2002 mL 26.0010 mL 52.0021 mL
5 mM 1.0400 mL 5.2002 mL 10.4004 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.2002 mL 26.0010 mL 52.0021 mL 130.0052 mL
5 mM 1.0400 mL 5.2002 mL 10.4004 mL 26.0010 mL
10 mM 0.5200 mL 2.6001 mL 5.2002 mL 13.0005 mL
15 mM 0.3467 mL 1.7334 mL 3.4668 mL 8.6670 mL
20 mM 0.2600 mL 1.3001 mL 2.6001 mL 6.5003 mL
25 mM 0.2080 mL 1.0400 mL 2.0801 mL 5.2002 mL
30 mM 0.1733 mL 0.8667 mL 1.7334 mL 4.3335 mL
40 mM 0.1300 mL 0.6500 mL 1.3001 mL 3.2501 mL
50 mM 0.1040 mL 0.5200 mL 1.0400 mL 2.6001 mL
60 mM 0.0867 mL 0.4334 mL 0.8667 mL 2.1668 mL
80 mM 0.0650 mL 0.3250 mL 0.6500 mL 1.6251 mL
100 mM 0.0520 mL 0.2600 mL 0.5200 mL 1.3001 mL
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(±)-Amiflamine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(±)-Amiflamine77502-96-6FLA 336FLA336FLA-336Monoamine OxidaseMAOInhibitorinhibitorinhibit

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