1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog
  3. Raluridine

Raluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

Raluridine Chemical Structure

Raluridine Chemical Structure

CAS No. : 119644-22-3

Size Price Stock Quantity
5 mg USD 980 In-stock
10 mg USD 1470 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Raluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Clinical Trial
Molecular Weight

264.64

Formula

C9H10ClFN2O4

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC[C@@H]1[C@@H](F)C[C@H](N2C(NC(C(Cl)=C2)=O)=O)O1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (944.68 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7787 mL 18.8936 mL 37.7872 mL
5 mM 0.7557 mL 3.7787 mL 7.5574 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.7787 mL 18.8936 mL 37.7872 mL 94.4680 mL
5 mM 0.7557 mL 3.7787 mL 7.5574 mL 18.8936 mL
10 mM 0.3779 mL 1.8894 mL 3.7787 mL 9.4468 mL
15 mM 0.2519 mL 1.2596 mL 2.5191 mL 6.2979 mL
20 mM 0.1889 mL 0.9447 mL 1.8894 mL 4.7234 mL
25 mM 0.1511 mL 0.7557 mL 1.5115 mL 3.7787 mL
30 mM 0.1260 mL 0.6298 mL 1.2596 mL 3.1489 mL
40 mM 0.0945 mL 0.4723 mL 0.9447 mL 2.3617 mL
50 mM 0.0756 mL 0.3779 mL 0.7557 mL 1.8894 mL
60 mM 0.0630 mL 0.3149 mL 0.6298 mL 1.5745 mL
80 mM 0.0472 mL 0.2362 mL 0.4723 mL 1.1808 mL
100 mM 0.0378 mL 0.1889 mL 0.3779 mL 0.9447 mL
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Raluridine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Raluridine
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HY-124092
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