Recombinant Humanized Type III Collagen 28.6kDa
Based on 1 Customer Validation
Recombinant Humanized Type III Collagen 28.6kDa is a 28.6 kDa recombinant humanized type III collagen. Recombinant Humanized Type III Collagen possesses a variety of biological functions, such as promoting the regeneration of the skin extracellular matrix and improving the cellular microenvironment. Recombinant Humanized Type III Collagen can also inhibit the proliferation, migration and invasion of breast cancer cells. Recombinant Humanized Type III Collagen plays a role in cell adhesion, migration, proliferation and differentiation by interacting with Integrin.
For research use only. We do not sell to patients.
- Purity: 95.00%
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Recombinant Humanized Type III Collagen can significantly inhibit the proliferation, migration, invasion and autophagy of various breast cancer cells, induce cell apoptosis and dormancy, and is non-toxic to normal breast epithelial cells, and this effect depends on the DDR1 pathway[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Color White to off-white
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SMILES
[Recombinant Humanized Type III Collagen 28.6kDa]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (263 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
[1]. Liu X, et al., Recombinant humanized collagen type III with high antitumor activity inhibits breast cancer cells autophagy, proliferation, and migration through DDR1. Int J Biol Macromol. 2023 Jul 15;243:125130. [Content Brief]
[2]. Kuivaniemi H, et al. Type III collagen (COL3A1): Gene and protein structure, tissue distribution, and associated diseases. Gene. 2019 Jul 30;707:151-171. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)