2. Metabolic Enzyme/Protease
  3. Tyrosinase
  4. (rel)-β-Tocopherol

(rel)-β-Tocopherol is a relative configuration of β-Tocopherol. β-Tocopherol is a lipid-soluble form of vitamin E with antioxidant activity.

For research use only. We do not sell to patients.

(rel)-β-Tocopherol

(rel)-β-Tocopherol Chemical Structure

CAS No. : 148-03-8

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of (rel)-β-Tocopherol:

(rel)-β-Tocopherol Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

(rel)-β-Tocopherol is a relative configuration of β-Tocopherol. β-Tocopherol is a lipid-soluble form of vitamin E with antioxidant activity[1].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

β-Tocopherol (50 μM, 48 h) slightly inhibits A7r5 (10% inhibition) and CHO cell (20% inhibition) proliferation, while showing no inhibition against HeLa cells[2].
β-Tocopherol (50 μM, 24 h) inhibits PMA (HY-18739)-induced adhesion of human erythroleukemia (HEL) cells (11% inhibition), and inhibits the expression of integrins α4 and α5 on cell surface[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(rel)-β-Tocopherol Related Antibodies

Cell Proliferation Assay[2]

Cell Line: A7r5, CHO, HeLa cells
Concentration: 50 μM
Incubation Time: 48 h
Result: Slightly inhibited A7r5 and CHO cell proliferation.
Did not inhibit HeLa cell proliferation.
Molecular Weight

416.69

Formula

C28H48O2
CAS No.
Appearance

Solid-Liquid Mixture

Color

Colorless to off-white

SMILES

OC1=CC(C)=C2C(CC[C@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)O2)=C1C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

Ethanol : 50 mg/mL (119.99 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3999 mL 11.9993 mL 23.9987 mL
5 mM 0.4800 mL 2.3999 mL 4.7997 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% EtOH    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 1.25 mg/mL (3.00 mM); Clear solution

    This protocol yields a clear solution of ≥ 1.25 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (12.5 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.91%

SDS (913 KB)

COA (242 KB) HNMR (130 KB) RP-HPLC (115 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol 1 mM 2.3999 mL 11.9993 mL 23.9987 mL 59.9966 mL
5 mM 0.4800 mL 2.3999 mL 4.7997 mL 11.9993 mL
10 mM 0.2400 mL 1.1999 mL 2.3999 mL 5.9997 mL
15 mM 0.1600 mL 0.8000 mL 1.5999 mL 3.9998 mL
20 mM 0.1200 mL 0.6000 mL 1.1999 mL 2.9998 mL
25 mM 0.0960 mL 0.4800 mL 0.9599 mL 2.3999 mL
30 mM 0.0800 mL 0.4000 mL 0.8000 mL 1.9999 mL
40 mM 0.0600 mL 0.3000 mL 0.6000 mL 1.4999 mL
50 mM 0.0480 mL 0.2400 mL 0.4800 mL 1.1999 mL
60 mM 0.0400 mL 0.2000 mL 0.4000 mL 0.9999 mL
80 mM 0.0300 mL 0.1500 mL 0.3000 mL 0.7500 mL
100 mM 0.0240 mL 0.1200 mL 0.2400 mL 0.6000 mL
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(rel)-β-Tocopherol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(rel)-β-Tocopherol148-03-8Tyrosinaseβ-Tocopherolvitamin EantioxidantInhibitorinhibitorinhibit

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