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Cat. No.: HY-162880

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RIPK1-IN-24

RIPK1-IN-24 is a receptor-interacting protein kinase 1 (RIPK1) inhibitor with an IC₅₀ value of 1.3 μM. RIPK1-IN-24 can be used for research on inflammatory diseases.

For research use only. We do not sell to patients.

CAS No.: 1358585-26-8
Formula: C₂₆H₂₁FN₆O₂
Molecular Weight:468.48

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

RIPK1-IN-24 Chemical Structure

CAS No.: 1358585-26-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

RIPK1-IN-24 is a receptor-interacting protein kinase 1 (RIPK1) inhibitor with an IC₅₀ value of 1.3 μM. RIPK1-IN-24 can be used for research on inflammatory diseases^[1].

All RIP kinase Isoforms :

Chemical Information

CAS No. 1358585-26-8
Molecular Weight 468.48
Formula C₂₆H₂₁FN₆O₂
SMILES

O=C(NC1=CC=C(CN2C=NC(C3=NC(C4=CC=CC(F)=C4)=NO3)=C2)C=C1)NCC5=CC=CC=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yu Y, et al. Discovery of 5-(1-benzyl-1H-imidazol-4-yl)-1,2,4-oxadiazole derivatives as novel RIPK1 inhibitors via structure-based virtual screening. Drug Dev Res. 2024 Aug;85(5):e22235. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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RIPK1-IN-24

All RIP kinase Isoforms

Biological Activity

Description

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

RIPK1-IN-24 Related Classifications

HY-162880 Related Classifications

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