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Cat. No.: HY-162880

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RIPK1-IN-24

RIPK1-IN-24 is a receptor-interacting protein kinase 1 (RIPK1) inhibitor with an IC₅₀ value of 1.3 μM. RIPK1-IN-24 can be used for research on inflammatory diseases.

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CAS No.: 1358585-26-8
Formule: C₂₆H₂₁FN₆O₂
Masse moléculaire:468.48

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

RIPK1-IN-24 Chemical Structure

CAS No.: 1358585-26-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

RIPK1-IN-24 is a receptor-interacting protein kinase 1 (RIPK1) inhibitor with an IC₅₀ value of 1.3 μM. RIPK1-IN-24 can be used for research on inflammatory diseases^[1].

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Chemical Information

CAS No. 1358585-26-8
Masse moléculaire 468.48
Formule C₂₆H₂₁FN₆O₂
SMILES

O=C(NC1=CC=C(CN2C=NC(C3=NC(C4=CC=CC(F)=C4)=NO3)=C2)C=C1)NCC5=CC=CC=C5
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Yu Y, et al. Discovery of 5-(1-benzyl-1H-imidazol-4-yl)-1,2,4-oxadiazole derivatives as novel RIPK1 inhibitors via structure-based virtual screening. Drug Dev Res. 2024 Aug;85(5):e22235. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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RIPK1-IN-24

Voir tous les produits spécifiques à Isoform RIP kinase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

RIPK1-IN-24 Related Classifications

HY-162880 Related Classifications