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Cat. No.: HY-N4331

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Rivulariapeptolides 1185

1 Cited Publications

Customer Review

Based on 1 publication(s) in Google Scholar

Rivulariapeptolides 1185 is a high potent and selective serine protease inhibitor with IC₅₀ values of 13.17 nM, 23.59 nM and 55.26 nM for chymotrypsin, elastase and proteinase K, respectively.

For research use only. We do not sell to patients.

Formula: C₆₁H₈₇N₉O₁₅
Molecular Weight:1186.39

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (278 KB)

Rivulariapeptolides 1185 Chemical Structure

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Publications (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

IC₅₀ & Target

IC50: 13.17 nM (chymotrypsin); 23.59 nM (elastase) and 55.26 nM (proteinase K)^[1].

In Vitro

Rivulariapeptolides 1185 (0-3 μM, 40 min) has high potency and distinct selectivity with IC₅₀ values of 13.17 nM, 23.59 nM and 55.26 nM for chymotrypsin, elastase and proteinase K, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Molecular Weight 1186.39
Formula C₆₁H₈₇N₉O₁₅
SMILES

CCCC(N1[C@H](C(N[C@H](C(N[C@H](C(NC(C(N[C@H]2CC[C@@H](O)[N@@]3C2=O)=O)CC(C)C)=O)[C@@H](C)OC([C@H](C(C)C)NC([C@H](CC4=CC=C(O)C=C4)N(C([C@@H]3CC5=CC=CC=C5)=O)C)=O)=O)=O)[C@H](OC([C@@H]6CCCN6C(CCC)=O)=O)C)=O)CCC1)=O
Structure Classification
- Others
Initial Source
- Microorganisms
Cyanobacteria
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Journal Impact Factor

Sci Rep

IL-36 activates neutrophil extracellular traps and exacerbates LPS-induced ARDS in mice. [Abstract]

2026 May 9;16(1):21231. PMID: 42103804

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (278 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Raphael Reher, et al. Native metabolomics identifies the rivulariapeptolide family of protease inhibitors. Nat Commun. 2022 Aug 8;13(1):4619. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Rivulariapeptolides 1185

1 Cited Publications

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Publications (1)
Purity & Documentation
References

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Rivulariapeptolides 1185

Publications Citing Use of MedChemExpress (MCE) Rivulariapeptolides 1185

Biological Activity

Chemical Information

Publications (1)

Purity & Documentation

References

Calculators

Help & FAQs

Rivulariapeptolides 1185 Related Classifications

HY-N4331 Related Classifications