RU-39411
RU-39411 is a steroidal anti-estrogen with mixed estrogenic/antiestrogen activity. RU-39411 has shown inhibitory effects on cell growth in the MCF-7 breast cancer model, with the effect being correlated with its binding affinity to the estrogen receptor. RU-39411 was able to downregulate the estrogen binding capacity of cells, but did not reduce estrogen receptor mRNA levels, indicating that the grafting of its side chain prevents the antagonistic effects usually associated with steroidal estrogens. The administration of RU-39411 can promote the synthesis of progesterone receptors, further supporting its activity as an estrogen.
For research use only. We do not sell to patients.
- CAS No.: 120382-04-9
- Formula: C28H37NO3
- Molecular Weight:435.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 120382-04-9
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Molecular Weight 435.60
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Formula C28H37NO3
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SMILES
C[C@@]12[C@H](CC[C@]1([C@@]3(CCC4=C([C@]3([C@H](C2)C5=CC=C(C=C5)OCCN(C)C)[H])C=CC(O)=C4)[H])[H])O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RU-39411 Related Classifications
HY-117649 Related Classifications
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