SARS-CoV-2-IN-18
SARS-CoV-2-IN-18 (Compound 26) is a potent SARS-CoV-2 3C-like protease inhibitor with an IC50 of 45 nM.
For research use only. We do not sell to patients.
- CAS No.: 184904-82-3
- Formula: C20H14N2O3
- Molecular Weight:330.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 45 nM (SARS-CoV-2 3C-like protease)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | EC50 |
>10 μM
Compound: 18
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Compound was tested for the antiviral activity against Human Rhinovirus -14(HRV-14) in HeLa cells
Compound was tested for the antiviral activity against Human Rhinovirus -14(HRV-14) in HeLa cells
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[PMID: 8978838] |
| Vero C1008 | CC50 |
<2.2 μM
Compound: L-26; 6
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Cytotoxicity against African green monkey Vero E6 assessed as inhibition of cell growth incubated for 26 hrs
Cytotoxicity against African green monkey Vero E6 assessed as inhibition of cell growth incubated for 26 hrs
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[PMID: 37859715] |
Chemical Information
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CAS No. 184904-82-3
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Molecular Weight 330.34
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Formula C20H14N2O3
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SMILES
O=C(C1=CC2=C(N(CC3=CC=C4C=CC=CC4=C3)C(C2=O)=O)C=C1)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SARS-CoV-2-IN-18 Related Classifications
HY-143470 Related Classifications
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