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United States

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Cat. No.: HY-W668749

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3BP-3580

3BP-3580 (compound 11) is a conjugate targeting FAP that binds to FAP-positive cells via the FAPI moiety and internalizes, delivering the payload to FAP-expressing cells, thereby inhibiting RA FLS proliferation, migration, and invasion, reducing inflammatory cytokine expression, and suppressing pannus formation. 3BP-3580 can be used for research on rheumatoid arthritis.

For research use only. We do not sell to patients.

CAS No.: 2374782-82-6
Formula: C₂₉H₃₆F₂N₆O₅
Molecular Weight:586.63

Storage:

-20°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Data Sheet (272 KB)

3BP-3580 Chemical Structure

CAS No.: 2374782-82-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 2374782-82-6
Appearance Solid
Molecular Weight 586.63
Formula C₂₉H₃₆F₂N₆O₅
Color White to off-white
SMILES

O=C(N1[C@@H](CC(F)(C1)F)C#N)CNC(C2=CC=NC3=C2C=C(OCCCN4CCN(CC4)C(OC(C)(C)C)=O)C=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wang L, et al. Coupled drugs and their preparation methods and their application in the preparation of synovial drugs for the treatment of rheumatoid arthritis. CN116874545A. China. 2023.10.13.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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