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Cat. No.: HY-185346

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AChE-IN-113

AChE-IN-113 is a selective acetylcholinesterase inhibitor with a K_i value of 8.3 μM against electric eel acetylcholinesterase. AChE-IN-113 can be used for the research of Alzheimer's disease.

For research use only. We do not sell to patients.

CAS No.: 2365416-33-5
Formula: C₂₂H₂₂O₇
Molecular Weight:398.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

AChE-IN-113 Chemical Structure

CAS No.: 2365416-33-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Cholinesterase (ChE) Isoforms :

AChE
BChE

Chemical Information

CAS No. 2365416-33-5
Molecular Weight 398.41
Formula C₂₂H₂₂O₇
SMILES

O=C(OC(/C=C/C1=CC=C(OC)C=C1OC)=O)/C=C/C2=CC=C(OC)C=C2OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Animals and Diseases

Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Gießel JM, et al. Substituted cinnamic anhydrides act as selective inhibitors of acetylcholinesterase. Bioorg Chem. 2019;90:103058. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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