Tecnazene
Based on 1 Customer Validation
Tecnazene is a dinitroaromatic fungicide and plant growth regulator. Tecnazene binds irreversibly to human skin tissues and exhibits acute toxicity in Rattus norvegicus (brown rat). Tecnazene exerts sprouting-inhibiting and antifungal activities by inhibiting the sprouting of potato tuber buds and blocking the growth and reproduction of fungi that cause dry rot. Tecnazene has significant antifungal and sprouting-inhibiting activities, and shows high toxicity to aquatic organisms such as freshwater fish and crustaceans. Tecnazene is used for sprouting inhibition and dry rot control during potato storage.
For research use only. We do not sell to patients.
- Purity: 99.96%
- CAS No.: 117-18-0
- Formula: C6HCl4NO2
- Molecular Weight:260.89
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Tecnazene is mainly applied in the agricultural field as a dual-effect pesticide for sprouting inhibition and dry rot control during potato storage. It is also used in studies on the in vitro human skin permeation properties of highly lipophilic chlorinated aromatic compounds, as well as in the calibration and optimization of transdermal absorption and diffusion models[2].
In in vitro human skin permeation assays, the percutaneous absorption rate of Tecnazene reaches 22-33% under occlusive conditions and 2.2-6.1% under non-occlusive conditions[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Tecnazene shows high toxicity to aquatic organisms such as freshwater fish and crustaceans, with a 96-hour LC50 of 270-2340 μg/L[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 117-18-0
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Appearance Solid
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Molecular Weight 260.89
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Formula C6HCl4NO2
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Color White to off-white
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SMILES
ClC1=C(C(Cl)=C(C=C1Cl)Cl)[N+]([O-])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 200 mg/mL (766.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (277 KB)
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SDS (761 KB)
- English - EN (761 KB)
- Français - FR (761 KB)
- Deutsch - DE (761 KB)
- Norwegian - NO (761 KB)
- Español - ES (761 KB)
- Swedish - SV (761 KB)
- Italian - IT (761 KB)
- Korean - KR (761 KB)
- Portuguese - PT (761 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8330 mL | 19.1652 mL | 38.3303 mL | 95.8258 mL |
| 5 mM | 0.7666 mL | 3.8330 mL | 7.6661 mL | 19.1652 mL | |
| 10 mM | 0.3833 mL | 1.9165 mL | 3.8330 mL | 9.5826 mL | |
| 15 mM | 0.2555 mL | 1.2777 mL | 2.5554 mL | 6.3884 mL | |
| 20 mM | 0.1917 mL | 0.9583 mL | 1.9165 mL | 4.7913 mL | |
| 25 mM | 0.1533 mL | 0.7666 mL | 1.5332 mL | 3.8330 mL | |
| 30 mM | 0.1278 mL | 0.6388 mL | 1.2777 mL | 3.1942 mL | |
| 40 mM | 0.0958 mL | 0.4791 mL | 0.9583 mL | 2.3956 mL | |
| 50 mM | 0.0767 mL | 0.3833 mL | 0.7666 mL | 1.9165 mL | |
| 60 mM | 0.0639 mL | 0.3194 mL | 0.6388 mL | 1.5971 mL | |
| 80 mM | 0.0479 mL | 0.2396 mL | 0.4791 mL | 1.1978 mL | |
| 100 mM | 0.0383 mL | 0.1917 mL | 0.3833 mL | 0.9583 mL |
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