76 Results for "

duodenum

" in MedChemExpress (MCE) Product Catalog:
Products (76)

76 Results for "duodenum" in MCE Product Catalog:

6
6 Publications Verification
製品番号: HY-14289
CAS 番号: 51481-61-9
純度:  ≥98.0%
別名: SKF-92334
Cimetidine (SKF-92334) is an orally active, inverse and BBB-permeable histamine H2 receptor antagonist with a Ki of 0.6 μM. Cimetidine is a gastric acid reducer, and can be used for duodenal and gastric ulcers research. Cimetidine has anti-cancer and anti-inflammatory activity .
loading...
    loading...
4
4 Cited Publications
製品番号: HY-P0093
CAS 番号: 25126-32-3
別名: Cholecystokinin octapeptide; CCK-8; SQ19844
研究分野:  

Infection Cancer

Sincalide (Cholecystokinin octapeptide, CCK-8) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. Sincalide is a major bioactive segment of CCK that retains most of the biological activities of CCK. Sincalide can promote gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. Sincalide can increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum. Sincalide is a major bioactive segment of CCK that retains most of the biological activities of CCK .
loading...
    loading...
4
4 Cited Publications
製品番号: HY-P0093A
CAS 番号: 70706-98-8
別名: Cholecystokinin octapeptide ammonium; CCK-8 ammonium; SQ19844 ammonium
研究分野:  

Infection Cancer

Sincalide ammonium (Cholecystokinin octapeptide ammonium, CCK-8 ammonium) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. Sincalide ammonium is a major bioactive segment of CCK that retains most of the biological activities of CCK. CCK‐8 can promote gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. Sincalide ammonium can increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum. Sincalide ammonium is a major bioactive segment of CCK that retains most of the biological activities of CCK .
loading...
    loading...
1
1 Cited Publications
製品番号: HY-W008614
CAS 番号: 131926-99-3
別名: AG-1813
研究分野:  

Metabolic Disease

Lansoprazole sulfone (AG-1813) is an orally active and selective inhibitor of H +, K +-ATPase. Lansoprazole sulfone can significantly stimulates gastric acid secretion by inhibiting H +, K +-ATPase. Lansoprazole sulfone has potential applications in duodenal ulcer, gastric ulcer, gastroesophageal reflux disease and Zolinger Ellison disease .
loading...
    loading...
製品番号: HY-B2191
CAS 番号: 6223-35-4
別名: Guaiazulenesulfonate sodium
Target:  

Drug Derivative

研究分野:  

Inflammation/Immunology

Sodium gualenate (Guaiazulenesulfonate sodium) is a hydrophilic derivative of guaiazulene with excellent anti-inflammatory and wound-healing effects mainly used for the treatment of duodenal ulcer, gastric ulcer and gastritis.
loading...
    loading...
製品番号: HY-P11292
Target:  

Calcium Channel

研究分野:  

Cardiovascular Disease

Caloxin 1b3, a peptide, is a selective plasma membrane Ca 2+ pump 1 (PMCA1) inhibitor. Caloxin 1b3 significantly inhibits PMCA1 Ca 2+–Mg 2+-ATPase in the rabbit duodenal mucosa than the PMCA4 in the human erythrocyte ghosts. Caloxin 1b3 also increases cytosolic Ca 2+ concentration in endothelial cells. Caloxin 1b3 can be used for cardiovascular disorders research .
loading...
    loading...
製品番号: HY-B0305A
CAS 番号: 93793-83-0
別名: HOE 760
Roxatidine Acetate Hydrochloride is a potent, selective, competitive and orally active histamine H2-receptor antagonist. Roxatidine Acetate Hydrochloride has antisecretory potency against gastric acid secretion. Roxatidine Acetate Hydrochloride can also suppress inflammatory responses and can be used for gastric and duodenal ulcers research. Roxatidine Acetate Hydrochloride has antitumor activity .
loading...
    loading...
製品番号: HY-108278
CAS 番号: 1222-57-7
純度:  99.65%
Target:  

Drug Derivative

研究分野:  

Endocrinology

Zolimidine, a derivate of imidazopyridine, is an orally active antiulcer agent. Zolimidine stimulates mucus secretion in intestinal mucosal cells and enhacnes intestinal wall more resistant to ulceration. Zolimidine exhibits gastroprotective effect in duodenal ulcer research .
loading...
    loading...
製品番号: HY-109538
CAS 番号: 17034-35-4
純度:  99.16%
Secretin (swine), a neuroendocrine hormone, is the first hormone to be identifie and is secreted by S cells that are localized primarily in the mucosa of the duodenum. Secretin also is a 27-amino acid peptide, which acts on secretin receptors. Secretin is expressed by cells in all mature enteroendocrine cell subsets and can be prompted by fatty acids. Secretin stimulates the secretion of pancreatic water and bicarbonate. Secretin exerts various effects in organs, can be used for the research of digestive system, central nervous system and energy metabolism .
loading...
    loading...
製品番号: HY-N6655
CAS 番号: 3493-12-7
別名: DL-MMSC
DL-Methionine methylsulfonium chloride (DL-MMSC) is an orally effective methionine-derived sulfonium salt that promotes gastric emptying and gastrointestinal transit. DL-Methionine methylsulfonium chloride attenuates oxidative stress and inflammatory responses, and enhances anti-apoptotic (apoptosis) signaling, thereby ameliorating Sodium metabisulfite (HY-Y1326)-induced testicular dysfunction and semen quality impairment. DL-Methionine methylsulfonium chloride is applicable for research on functional dyspepsia, gastrointestinal motility, and male reproductive function injury .
loading...
    loading...
製品番号: HY-B2191R
CAS 番号: 6223-35-4
別名: Guaiazulenesulfonate sodium (Standard)
Sodium gualenate (Standard) is the analytical standard of Sodium gualenate. This product is intended for research and analytical applications. Sodium gualenate (Guaiazulenesulfonate sodium) is a hydrophilic derivative of guaiazulene with excellent anti-inflammatory and wound-healing effects mainly used for the treatment of duodenal ulcer, gastric ulcer and gastritis.
loading...
    loading...
製品番号: HY-14289R
CAS 番号: 51481-61-9
別名: SKF-92334 (Standard)
Cimetidine (Standard) is the analytical standard of Cimetidine. This product is intended for research and analytical applications. Cimetidine (SKF-92334) is an orally active and inverse histamine H2 receptor antagonist with a Ki of 0.6 μM. Cimetidine is a gastric acid reducer, and can be used for duodenal and gastric ulcers research. Cimetidine has anti-cancer and anti-inflammatory activity .
loading...
    loading...
製品番号: HY-137941
CAS 番号: 78273-80-0
純度:  98.25%
Roxatidine is an active metabolite of Roxatidine acetate hydrochloride, is an orally active histamine H2-receptor antagonist. Roxatidine, an anti-ulcer agent, suppresses histamine release (thus inhibiting proton secretion) and inhibits the production of VEGF-1, an important marker of inflammation and angiogenesis. Anti-allergic inflammatory effect. Roxatidine is promising for research of gastric and duodenal ulcers .
loading...
    loading...
製品番号: HY-B1719A
CAS 番号: 50-10-2
Target:  

mAChR

研究分野:  

Inflammation/Immunology

Oxyphenonium bromide is an antiacetylcholine compound. Oxyphenonium bromide is an antagonist of mAChR. Oxyphenonium bromide protects against the bronchial obstructive effects .
loading...
    loading...
製品番号: HY-108283
CAS 番号: 41826-92-0
純度:  99.83%
別名: AA 149; Supacal
Target:  

Calcium Channel

研究分野:  

Inflammation/Immunology

Trepibutone (AA 149) increases secretion of bile and pancreatic juice, and accelerates flaccidity of the smooth muscle in the gastrointestinal tract. Trepibutone can be used for the research of cholecystitis and functional gastrointestinal disorders .
loading...
    loading...
製品番号: HY-B1109R
CAS 番号: 32795-44-1
別名: Acecainide (Standard); NAPA (Standard)
Cimetidine (hydrochloride) (Standard) is the analytical standard of Cimetidine (hydrochloride). This product is intended for research and analytical applications. Cimetidine (SKF-92334) hydrochloride is an orally active and inverse histamine H2 receptor antagonist with a Ki of 0.6 μM. Cimetidine hydrochloride is a gastric acid reducer, and can be used for duodenal and gastric ulcers research. Cimetidine hydrochloride has anti-cancer and anti-inflammatory activity .
loading...
    loading...
製品番号: HY-106327
CAS 番号: 110205-60-2
Target:  

Motilin Receptor

研究分野:  

Metabolic Disease

EM-523 is a motilin agonist and an erythromycin derivative. EM-523 has pED50 values of 8.19 and 6.08 for promoting contractions in rabbit small intestinal tissue and human duodenal tissue, respectively. EM-523 can be used in the research of gastrointestinal diseases .
loading...
    loading...
製品番号: HY-169914
CAS 番号: 130152-35-1
別名: JO 1784 hydrochloride
Target:  

Sigma Receptor

Igmesine hydrochloride (JO 1784 hydrochloride) is a selective σ-1 receptor agonist (IC50 = 39 nM) with oral activity and blood-brain barrier penetration. Igmesine hydrochloride stimulates duodenal bicarbonate secretion in rats via a σ1/vagal/CCK-A-dependent pathway, without antisecretory activity. Igmesine hydrochloride centrally blocks CRF-mediated gastrin-inhibitory effects, and in TMT toxicity and MCAO focal ischemia models, it downregulates PTBBS, reduces NOS, and modulates M1/M2 density. Igmesine hydrochloride is used in research on duodenal ulcers, Alzheimer's disease, and related diseases .
loading...
    loading...
製品番号: HY-W983015
CAS 番号: 23130-26-9
Davidigenin is an antidiabetic compound with antitumor, antispasmodic, and antioxidant activities. Davidigenin inhibits duodenal contractions induced by acetylcholine or histamine.
loading...
    loading...
製品番号: HY-123819
CAS 番号: 568526-77-2
Target:  

CXCR

研究分野:  

Infection

KRH-1636 is a CXC chemokine receptor (CXCR) 4 antagonist. KRH-1636 can be used in HIV-1 research .
loading...
    loading...