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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
43 Results for "
DOPC/Chol LUVs
" in MedChemExpress (MCE) Product Catalog:
Products (43)
43 Results for "DOPC/Chol LUVs" in MCE Product Catalog:
12
Category:
Target:
1
1
1 Cited Publications
Cat. No.: HY-P75786
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GBA1; Acid Beta-Glucosidase; Prev. GLUC; Glucocerebrosidase; Prev. GBA; Glucosylceramidase; D-Glucosyl-N-Acylsphingosine Glucohydrolase; Imiglucerase; Lysosomal Cholesterol Glycosyltransferase; Alglucerase; Lysosomal Acid Glucosylceramidase; Beta-GC; Chol
Species:
Human
Source:
HEK293
Synonyms: DOPS-NA
1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium (DOPS-NA) is a ubstitute for Phosphoserine/phosphatidylserine. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can be used together with DOPC and DOPE in lipid mixtures for the synthesis of liposomes. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine sodium can self-assemble into single-layer or double-layer membrane structures, similar to cell membranes, and possesses high membrane fluidity and flexibility. 1,2-Dioleoyl-sn-glycero-3-phospho-L-serine is widely applied in membrane biology, cell membrane research, lipid preparation, and drug delivery systems .
Synonyms: DC-Cholesterol hydrochloride
Target:
Research Areas:
DC-Chol hydrochloride is a cationic lipid. DC-Chol hydrochloride could inhibit Aβ40 fibril formation under appropriate experimental conditions. DC-Chol hydrochloride strongly inhibits amyloidogenesis of oxidized hCT in a dose-dependent manner. DC-Chol hydrochloride induces the production of Th1 (IL-2 and IFN-γ) and Th2 (IL-5) cytokines. DC-Chol hydrochloride can enhance the body's immune response to antigens. DC-Chol hydrochloride is used as a gene delivery vector. DC-Chol hydrochloride can be used in research in areas such as hepatitis B vaccines to improve vaccine immunity .
Cat. No.: HY-144007
CAS No.: 27321-96-6
Chol-PEG is an amphiphilic cholesterol-polyethylene glycol conjugate and also a liposomelike surface modifier. After Chol-PEG is incorporated into liposomelike vesicles, it forms a hydrophilic barrier on their surface, increases the thickness of the bound water layer around the liposomelike vesicles, and enhances the release rate of encapsulated compounds. Chol-PEG can be used as a modifier to prepare nonionic surfactant vesicles (liposomelike vesicles) for drug delivery applications .
Cat. No.: HY-113424AS
Purity: ≥98.0%
Synonyms: DOPC-d9
Synonyms: 3-Hexanoyl-NBD-Cholesterol
Target:
Research Areas:
3-C6-NBD-cholesterol is a fluorescent analog of Chol that can be used to measure the kinetics of membrane and intracellular trafficking .
Synonyms: ARO-AAT sodium
Target:
Research Areas:
Fazirsiran sodium is a second-generation RNAi agent. Fazirsiran sodium consistes of a cholesterol-conjugated RNAi trigger (chol-RNAi) to selectively degrade Alpha1-antitrypsin (AAT) mRNA by RNAi and a melittin-derived peptide conjugated to N-acetylgalactosamine (NAG) formulated as the excipient EX1 to promote endosomal escape of the chol-RNAi in hepatocytes . Fazirsiran sodium can be used in the study of Alpha-1 Antitrypsin Deficiency (AATD) liver disease. AATD is caused by mutations in the alpha-1 antitrypsin (SERPINA1) gene.
Cat. No.: HY-132604
CAS No.: 2175009-08-0
Synonyms: ARO-AAT
Target:
Research Areas:
Fazirsiran (ARO-AAT) is a second-generation RNAi agent. Fazirsiran consistes of a cholesterol-conjugated RNAi trigger (chol-RNAi) to selectively reduce Alpha1-antitrypsin (AAT) synthesis and a melittin-derived peptide conjugated to N-acetylgalactosamine (NAG) formulated as the excipient EX1 to promote endosomal escape of the chol-RNAi in hepatocytes . Fazirsiran can be used in the study of Alpha-1 Antitrypsin Deficiency (AATD) liver disease. Alpha-1 antitrypsin deficiency (AATD) is caused by mutations in the alpha-1 antitrypsin (SERPINA1) gene.
Cat. No.: HY-159859
CAS No.: 191990-35-9
IZ-Chol (IZ-Cholesterol) is an ionizable cationic lipid containing cholesterol. IZ-Chol-LNPs is highly potential to effectively complex with DNA, and endosome escape mechanisms mediated by proton sponge effect .
Cat. No.: HY-152901
CAS No.: 2106868-12-4
Target:
Research Areas:
Chol-N3 is a bioorthogonal-based chol probe. Chol-N3 can combine with super-resolution fluorescence microscopy (SRM), providing direct visualization of nanoscale lipid heterogeneity in the cell surface of resting living cells . Chol-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-N15913
CAS No.: 84366-67-6
Category:
Target:
Cat. No.: HY-149664
CAS No.: 137056-72-5
Synonyms: DC-Chol
3β-[N-(N′,N′-Dimethylaminoethyl)carbamoyl]cholesterol, a lipid, has been investigated in cancer gene therapy and vaccine delivery system .
Cat. No.: HY-125529
CAS No.: 184582-91-0
Synonyms: Chol-T
DMPAC-Chol (Chol-T) is used for liposome formation. DMPAC-Chol (Chol-T) liposomes exhibits great transfection effciencies .
Cat. No.: HY-112752
CAS No.: 219850-70-1
Gal-C4-Chol is a glycosylated cholesterol derivative. Gal-C4-Chol can be used as a ligand for asialoglycoprotein receptors (ASGPR) to prepare Galactosylated (Gal) liposomes. Gal-C4-Chol can be used to prepare simple lipid-based nanoparticles .
Cat. No.: HY-136869
CAS No.: 1027801-74-6
MHAPC-Chol, a cationic cholesterol, results in a high gene silencing effect via high cellular association. MHAPC-Chol delivers siRNA to the liver .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
