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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2199 Results for "
D4
" in MedChemExpress (MCE) Product Catalog:
Products (2199)
2199 Results for "D4" in MCE Product Catalog:
Cat. No.: HY-101384
CAS No.: 189744-46-5
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Research Areas:
Ro 10-5824 is a potent and selective D4R partial agonist with a Ki of 5.2 nM. Ro 10-5824 increases novel object exploration in C57 mice .
Cat. No.: HY-169020
CAS No.: 2375196-54-4
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SL agonist 1 is a Strigolactone (SL) agonist. SL agonist 1 can be recognized by the SL receptors OmKAI2d3 and OmKAI2d4, promoting the germination of Arabidopsis seeds .
Cat. No.: HY-17390BS
CAS No.: 1246820-19-8
Cat. No.: HY-W002114
CAS No.: 2374-03-0
Cat. No.: HY-101803R
CAS No.: 445295-04-5
Research Areas:
CP671305 (Standard) is the analytical standard of CP671305 (HY-101803). This product is intended for research and analytical applications. CP671305 is a potent, orally active, selective inhibitor of phosphodiesterase-4-D, and possesses high activities.
Cat. No.: HY-115946
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Research Areas:
Complex III-IN-2 (Compd 4d-2) is a complex III inhibitor. Complex III-IN-2 shows antifungal activity with an EC50 of 29.98 mg/L and 29.31 mg/L against sclerotinia sclerotiorum and R. solani, respectively .
Cat. No.: HY-146631S
CAS No.: 221093-38-5
Cat. No.: HY-18137
CAS No.: 1331782-27-4
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PF-04995274 is a potent, high-affinity, orally active and partial serotonin 4 receptor (5-HT4R) agonist. PF-04995274 has an EC50 range of 0.26-0.47 nM for human 5-HT4A/4B/4D/4E (Ki range of 0.15-0.46 nM), and has an EC50 range of 0.59-0.65 nM for rat 5-HT4S/4L/4E (Ki of 0.30 nM for rat 5-HT4S). PF-04995274 is brain penetrant and can be used for cognitive disorders associated with Alzheimer's disease .
Cat. No.: HY-168558
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Research Areas:
PDE4B/D-IN-4 (compound 4p) is a potent inhibitor of PDE-4B and PDE-4D, with IC50s of 5.50 nM and 6.81 nM, respectively. PDE4B/D-IN-4 shows an increase in the level of intracellular cAMP .
Cat. No.: HY-187840
CAS No.: 194038-94-3
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RBI257 is a selective dopamine D4R antagonist with a pKi of 8.42 for the hD4.4 receptor. RBI257 acts as a competitive antagonist at the hD4.4 receptor, blocking dopamine-stimulated G protein activation and GIRK current activation. RBI257 can be used for research on hypertension and schizophrenia .
Cat. No.: HY-152556
CAS No.: 2305415-96-5
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3-Deaza-4’-C-methyluridine, 4-Hydroxy-1-β-D-(4-C-methylribofuranosyl)-2(1H)-pyridinone is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
Cat. No.: HY-108751R
CAS No.: 1259305-29-7
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Aripiprazole Lauroxil (Standard) is the analytical standard of Aripiprazole Lauroxil. This product is intended for research and analytical applications. Aripiprazole lauroxil, an N-acyloxymethyl proagent of Aripiprazole (HY-14546), is a Long-acting injectable (LAI) typical antipsychotic for schizophrenia and a ligand of dopamine receptor D2R/D4R. Aripiprazole lauroxil is cleaved by body’s enzyme esterase to N-hydroxymethyl aripiprazole (plus lauric acid) and then to aripiprazole (plus formaldehyde), no toxicity.
Cat. No.: HY-123828
CAS No.: 389080-71-1
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Research Areas:
MLS6585 is a selective D1 dopamine receptor (D1R) positive allosteric modulator that enhances Dopamine (HY-B0451)-stimulated G protein/β-arrestin signaling and affinity without intrinsic D1R agonist activity. MLS6585 is inactive at D2R, D3R, D4R, and β2-adrenergic receptors. MLS6585 partially restores signaling of loss-of-function DRD1 variants and enhances responses to multiple agonists [4].
Cat. No.: HY-167959
CAS No.: 26544-20-7
MCPA-isooctyl is a selective conductive phenoxycarboxylate herbicide and an alternative to 2,4-D Butyl ester (HY-B0867). MCPA-isooctyl effectively controls broadleaf weeds in various crop fields via post-emergence foliar or soil treatment. MCPA-isooctyl is absorbed by the roots, stems and leaves of plants; it is easily metabolized and detoxified in gramineous crops, but difficult to metabolize in dicotyledonous weeds, causing stem and leaf distortion, root deformation, and eventually weed death. When formulated into chitosan nanoparticles, MCPA-isooctyl still significantly inhibits the growth of weeds in wheat fields, and reduces their chlorophyll content and biomass at low doses .
Cat. No.: HY-P7625
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: B2M; Beta 2-Microglobulin; Beta-2-Microglobulin; Beta-2-Microglobin; Beta Chain Of MHC Class I Molecules; AMYLD6; Beta 2-Microglobulin Protein; MHC1D4; Human Nkt Tcr Alpha Chain; IMD43; Human Nkt Tcr Beta Chain
Species:
Human
Source:
E. coli
Cat. No.: HY-P992433
OR502 is a humanized IgG1 monoclonal antibody targeting LILRB2 (ILT4/CD85d), with a Kd value of 1.18 nM. OR502 binds to LILRB2 with high affinity and blocks its interaction with HLA class I ligands, relieving myeloid cell-mediated immunosuppression, restoring CD8 + T cell function, and reprogramming the immunosuppressive macrophage phenotype, thereby simultaneously enhancing both innate and adaptive antitumor immune responses. OR502 can be used in the research of cancers and advanced cancers (including melanoma, non-small cell lung cancer, sarcoma/soft tissue cancer, and urothelial carcinoma) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
