407 Results for "

mixture

" in MedChemExpress (MCE) Product Catalog:
Products (407)

407 Results for "mixture" in MCE Product Catalog:

Cat. No.: HY-167680
CAS No.: 483369-58-0
Synonyms: GSK823093
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Denagliptin (GSK823093) is a small molecule dipeptidyl peptidase IV (DPP-4) inhibitor with activity for the suppression of endocrine and metabolic diseases. Denagliptin can be used to study type 2 diabetes. Denagliptin is stable in the solid state but degrades in solution and in mixtures with various excipients. Denagliptin also exhibits degradation in capsules, mainly through cyclization reactions to form (3S,7S,8aS) aminoamines to provide further synthetic materials. The degradation pathway of Denagliptin was elucidated, providing data to support its formulation development and regulatory filings .
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Cat. No.: HY-173630A
Research Areas:  

Cancer

(R)-BMS-986449 is the racemic mixture of BMS-986449 (HY-173630). BMS-986449 is a CELMoD molecular glue and an IKZF2/IKZF4 degrader. BMS-986449 targets the degradation of transcription factors Helios (IKZF2) and Eos (IKZF4) in regulatory T (Treg) cells. BMS-986449 redirects the E3 ubiquitin ligase Cereblon to induce the degradation of Helios and Eos, reprogramming Treg cells and enhancing antitumor immunity. BMS-986449 is promising for research of advanced solid tumors .
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Cat. No.: HY-N13772
CAS No.: 55812-91-4
Synonyms: (+)-Dihydroisorhamnetin
3'-O-Methyltaxifolin ((+)-Dihydroisorhamnetin) is a dihydroflavanol found in Pulicaria jaubertii. A mixture of these alcohol compounds including 3'-O-Methyltaxifolin found in Pulicaria jaubertii exhibits antitumor activity with IC50 values ​​of 19.1 μg, 20.0 μg, and 24.1 μg against prostate cancer (PC-3), breast cancer (MCF-7), and hepatocellular carcinoma (HepG-2) cell lines, respectively. Furthermore, 3'-O-Methyltaxifolin can induce cell apoptosis, making it a promising candidate for anticancer research. .
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Cat. No.: HY-W133898
CAS No.: 73049-73-7
Tryptone is a peptide-rich bacterial culture medium component that can regulate bacterial cell surface proteins and biofilm-related genes. Tryptone promotes the expression and assembly of bacterial adhesion proteins (such as LapA and LapF) by providing peptide substances as structural factors, enhancing cell surface hydrophobicity and intercellular adhesion, thereby stabilizing the biofilm matrix and supporting the maturation and maintenance of bacterial biofilms. The peptide mixture contained in Tryptone can specifically regulate the transcription of bacterial adhesion-related genes (such as activating LapA and inhibiting LapF), affecting the synthesis and localization of biofilm structural proteins .
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Cat. No.: HY-W700621
CAS No.: 1189959-10-1
Synonyms: Tris(2-​carboxyethyl)​phosphine hydrochloride-d12
TCEP-d12 (hydrochloride) (Tris(2-?carboxyethyl)?phosphine hydrochloride-d12) is deuterium labeled TCEP (hydrochloride). TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that is more stable and produces a faster S-S reductive reaction than other chemical reductants. TCEP hydrochloride is a trialkylphosphine, selectively reduces protein disuldes without altering the properties or interacting with thiol-directed agents in the reaction mixture. TCEP hydrochloride is also a commonly used reducing agent in the DNA/AuNP chemistry .
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Cat. No.: HY-W747104
CAS No.: 52957-16-1
Target:  

Sex Pheromone

(9E)-Tetradecen-1-ol is a pheromone that has no significant sexual attraction when used alone and can be secreted from the abdomen of the female Bertha armyworm moth (Mamestra configurata (Walker)). Isolate in tip extract to get in isolate. Another pheromone (Z)-11-hexadecen-1-ol was also isolated at the same time. Only when the two pheromones are mixed do they show male attraction (the ratio of C16:C14 in the mixture is about 19:1). optimal) .
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Cat. No.: HY-103019A
CAS No.: 1610358-53-6
Purity:  99.87%
Synonyms: (±)-BAY-1251152; (±)-VIP152
Research Areas:  

Cancer

(±)-Enitociclib ((±)-BAY-1251152) is the racemic mixture of Enitociclib (HY-103019E). Enitociclib is a selective CDK9 inhibitor and apoptosis inducer. Enitociclib inhibits CDK9 activity and reduces the phosphorylation of Ser2 in the carboxyl-terminal domain (CTD) of RNA polymerase Pol II, thereby downregulating the transcription of key oncogenes such as MYC and MCL1. Enitociclib has anti-proliferative activity targeting MYC + lymphoma and multiple myeloma (MM) cells, and has synergistic effects with Bortezomib (HY-10227) and Lenalidomide (HY-A0003), and can be used in the research of hematological malignancies .
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Cat. No.: HY-117215
CAS No.: 13877-91-3
Purity:  ≥90.0%
Beta-Ocimene is a naturally occurring organic compound that belongs to the terpene family. β-Ocimene exists as a mixture of two isomers: cis-β-ocimene and trans-β-ocimene. Possessing a pleasant, sweet, and herbaceous aroma, β-ocimene is found in many plants, including mint, basil, parsley, and kumquat. Due to its distinctive scent and flavor, β-ocimene is widely used in the fragrance and flavor industries. It also holds potential applications in agriculture as a natural insect repellent and as a pheromone that attracts beneficial insects. Additionally, β-ocimene exhibits potential anti-inflammatory and anti-cancer activities.
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Cat. No.: HY-126404
CAS No.: 65072-00-6
Casein hydrolysate is an orally effective, multi-functional mixture of bioactive peptides, a hydrolysis product of casein (HY-125865), containing ACE inhibitors and immunomodulatory target regulators, among others. Casein hydrolysate releases short-chain bioactive peptides through enzymatic hydrolysis of casein, increasing cellular glutathione and catalase levels, enhancing ConA-induced IL-2 production, and exhibiting metal ion chelation, free radical scavenging, antibacterial, and mineral absorption-promoting effects. Casein hydrolysate lowers blood pressure by inhibiting angiotensin-converting enzyme (ACE) and reducing bradykinin degradation .
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Cat. No.: HY-129836R
CAS No.: 26889-93-0
Research Areas:  

Infection

L-Amoxicillin (Standard) is the analytical standard of L-Amoxicillin. This product is intended for research and analytical applications. L-Amoxicillin is an antibiotic with activity against a wide range of bacterial infections. L-Amoxicillin is commonly used in antibacterial combinations when used in combination with the β-lactamase inhibitor potassium clavulanic acid. The related substances analysis method for L-Amoxicillin has been developed and validated according to the International Conference on Harmonization (ICH) guidelines, ensuring its effectiveness and accuracy in mixtures. L-Amoxicillin and some of its impurities have been further analyzed in stress testing and stability studies, providing support for optimizing its application .
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Cat. No.: HY-134200A
Research Areas:  

Metabolic Disease

1-Palmitoyl-2-oleoyl-sn-glycerol, 1-Oleoyl-3-palmitoylglycerol (1:1) is a 1:1 mixture of 1-Palmitoyl-2-oleoyl-sn-glycerol (HY-134200) and 1-Oleoyl-3-palmitoylglycerol (HY-W583685). 1-Palmitoyl-2-oleoyl-sn-glycerol, 1-Oleoyl-3-palmitoylglycerol (1:1) is the major active component of diacylglycerol (DAG) and a hypoxia-inducible factor (HIF) inducer .
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Cat. No.: HY-162596A
CAS No.: 863638-93-1
Synonyms: (Rac)-BA-1049
Target:  

ROCK

Research Areas:  

Neurological Disease

(Rac)-NRL-1049 is the racemic mixture of NRL-1049 (BA-1049 (free base)) (HY-162596). NRL-1049 is an orally available and selective ROCK2 inhibitor with IC50 values of 0.59 µM for ROCK2 and 26 µM for ROCK1, respectively. NRL-1049 modulates ROCK signaling, preserves blood-brain barrier integrity, reduces edema, seizures and hemorrhage, and alleviates cerebral cavernous malformation lesion burden. NRL-1049 can be used for the study of acute brain injury, ischemic stroke, and cerebral cavernous malformations .
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Cat. No.: HY-N0120
CAS No.: 65914-17-2
Synonyms: (E/Z)-Piceid
(E/Z)-Polydatin ((E/Z)-Piceid) is a mixture of the E/Z configurations of Polydatin (HY-N0120A). Polydatin can be isolated from Polygonum cuspidatum, grapes, peanuts, red wine, hop pellets, cocoa-containing products and chocolate products. Polydatin exhibits multiple biological properties, such as anti-platelet aggregation, anti-low-density lipoprotein oxidation, cardioprotective activity, anti-inflammatory and immunomodulatory functions. Polydatin shows favorable cytotoxic effects against various tumor cell lines, including cervical cancer cells, liver cancer cells, and nasopharyngeal carcinoma cells .
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Cat. No.: HY-N16865
Myristinin B/C is a mixture of Myristinin B and Myristinin C. Myristinin B/C is a flavan compound found in Horsfieldia amygdaline and Myristica cinnamomea. Myristinin B/C can selectively inhibit COX-2 activity with an IC50 of 2.1 μg/mL. Myristinin B/C can reduce the production of prostaglandin E2 (PGE2) and inhibit phospholipase A2 (PLA2), thereby blocking the release of inflammatory mediators. Myristinin B/C can inhibit Candida albicans with an IC50 of 6 μg/mL. Myristinin B/C can be used for the research of inflammation and infection, such as rheumatoid arthritis .
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Cat. No.: HY-W010807
CAS No.: 540-10-3
Hexadecyl palmitate is an organic compound commonly used in the cosmetic industry as an emollient, thickener and skin conditioning agent. Cetyl palmitate is derived from a mixture of cetyl alcohol (a fatty alcohol) and palmitic acid (a saturated fatty acid). It is often used in skin care products such as moisturizers, lotions, and creams to improve their texture and Helps them glide smoothly on the skin. In addition to its use in cosmetics, cetyl palmitate is used in other industries including pharmaceuticals, food additives and lubricants. Overall, it's considered safe for use in personal care products, but like any other ingredient, it may cause irritation or an allergic reaction in some people.
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Cat. No.: HY-W108862
CAS No.: 66204-44-2
Target:  

Bacterial

Research Areas:  

Infection

3,3'-Methylenebis[5-methyloxazolidine] is a bisoxazolidine-based hydrogen sulfide scavenger and fungicide derived from monoisopropanolamine (MIPA). 3,3'-Methylenebis[5-methyloxazolidine] exists as a mixture of structural isomers. 3,3'-Methylenebis[5-methyloxazolidine] is oil-soluble and serves as an oil-soluble alternative to hydrated hexahydrotriazine-based scavengers. 3,3'-Methylenebis[5-methyloxazolidine] can scavenge hydrogen sulfide and methanethiol via chemical reactions, and its scavenging efficiency increases after hydrolysis to MIPA-triazine in water .
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Cat. No.: HY-W743258
L-Amoxicillin-d4 sodium is the deuterium labeled L-Amoxicillin (HY-129836). L-Amoxicillin is an antibiotic with activity against a wide range of bacterial infections. L-Amoxicillin is commonly used in antibacterial combinations when used in combination with the β-lactamase inhibitor potassium clavulanic acid. The related substances analysis method for L-Amoxicillin has been developed and validated according to the International Conference on Harmonization (ICH) guidelines, ensuring its effectiveness and accuracy in mixtures. L-Amoxicillin and some of its impurities have been further analyzed in stress testing and stability studies, providing support for optimizing its application .
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Cat. No.: HY-K6022

MCE ECM Gentle Dissociation Solution is a gentle ECM-degrading enzyme mixture derived from marine bacteria and Bacillus species, specifically formulated for efficient and low-damage digestion of in-vitro cell systems. It selectively degrades extracellular matrix components while minimizing disruption to the cell membrane and intercellular junctions, thereby significantly reducing mechanical stress during dissociation. This product is compatible with a wide range of cell types, including stem cell colonies, primary cells, neural cells, and organoids, and is particularly well suited for gentle yet effective dissociation of brain organoids and other complex 3D structures.

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Cat. No.: HY-113764R
CAS No.: 98426-48-3
Synonyms: (Rac)-C4-HSL (Standard)
N-Butanoyl-DL-homoserine lactone (Standard) is the analytical standard of N-Butanoyl-DL-homoserine lactone. This product is intended for research and analytical applications. N-Butanoyl-DL-homoserine lactone ((Rac)-C4-HSL) is a racemic mixture of N-Butanoyl-D-homoserine lactone and N-Butanoyl-L-homoserine lactone. N-Butanoyl-L-homoserine lactone is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm. N-Butanoyl-L-homoserine lactone aptamers blocks qurom sensing and inhibits biofilm formation in Pseudomonas aeruginosa .
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Cat. No.: HY-121149B
CAS No.: 165813-01-4
Synonyms: (E/Z)-3-Hydroxytamoxifen
Research Areas:  

Cancer

(E/Z)-Droloxifene is a mixture of (E)-droloxifene (a selective estrogen receptor modulator) and (Z)-droloxifene. (E)-Droloxifene binds to the estrogen receptor (ER) with an IC50 value of 24 nM in rabbit uterine homogenates. (E)-Droloxifene increases uterine weight in immature rats, and reduces estradiol-induced increases in uterine weight in juvenile rats. (E)-Droloxifene also inhibits 17β-estradiol-stimulated growth of MCF-7, ZR-75-1, and T47D human breast cancer cells. (Z)-Droloxifene binds weakly to ER and has no estrogenic or antiestrogenic activity .
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