80 Results for "

Caspase substrate

" in MedChemExpress (MCE) Product Catalog:
Products (80)

80 Results for "Caspase substrate" in MCE Product Catalog:

Cat. No.: HY-P5348
CAS No.: 921771-40-6
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Ac-LEHD-pNA is a biological active peptide. (Caspase-9 substrate; pNA (4-nitroaniline)-derived caspase substrates are widely used for the colorimetric detection of various caspase activities. Cleavage of pNA peptides by caspases generates pNA that is monitored colorimetrically at ~405 nm. pNA has maximum absorption around 408 nm.)
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Cat. No.: HY-P4429
CAS No.: 201608-13-1
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Z-YVAD-AFC is a fluorescent substrate for Caspase-1, which can be used to detect and measure the activity of Caspase-1 .
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Cat. No.: HY-P3115
CAS No.: 1092077-23-0
Research Areas:  

Others

Ac-LEVD-AFC is capspase-4 fluorogenic substrate peptide that can be used for caspase-4 activity studies .
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Cat. No.: HY-P2016
CAS No.: 355140-49-7
Target:  

Proteasome

Research Areas:  

Others

Ac-Nle-Pro-Nle-Asp-AMC is a specific substrate for 26S proteasome. Ac-Nle-Pro-Nle-Asp-AMC can be used for the 26S proteasome caspase-like activity analysis .
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Cat. No.: HY-P10145
CAS No.: 189684-49-9
Research Areas:  

Others

Ac-LEVD-pNA is a chromogenic substrate for caspase-4 and can be used to detect caspase-4 activity .
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Cat. No.: HY-B1751S
CAS No.: 1267657-68-0
Quinidine-d3 is the d3-labeled Quinidine (15% dihydroquinidine) (HY-B1751). Quinidine (15% dihydroquinidine) is an orally active antiarrhythmic agent. Quinidine (15% dihydroquinidine) reduces the expression level of P-gp, inhibits P-gp-mediated efflux, increases the intracellular accumulation of P-gp substrates, induces PARP cleavage and Caspase-3 activation, and elevates the proportion of Apoptotic cells at the sub-G1 phase. Quinidine (15% dihydroquinidine) exerts sustained block and open-channel block effects on IK(f). Quinidine (15% dihydroquinidine) alters the urinary metabolic ratio of Amphetamine, modulates the Pentylenetetrazol-induced seizure threshold, and regulates the anticonvulsant effect of Dextromethorphan. Quinidine (15% dihydroquinidine) can be used in studies related to uterine sarcoma and seizures .
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Cat. No.: HY-P2617
CAS No.: 210344-99-3
Target:  

Caspase

Research Areas:  

Inflammation/Immunology Cancer

Ac-WEHD-AFC is a fluorogenic caspase-1 substrate. Ac-WEHD-AFC can measure caspase-1 fluorogenic activity and can be used for the research of tumor and inflammation .
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Cat. No.: HY-P2208
CAS No.: 219138-02-0
Target:  

Fluorescent Dye

Research Areas:  

Cancer

Z-IETD-AFC, a specific fluorescence substrate, can be used to determine the caspase-8 catalytic activity .
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Cat. No.: HY-P2616A
Research Areas:  

Others

Mca-YVADAP-Lys(Dnp)-OH TFA is a fluorogenic substrate for caspase-1 and angiotensin-converting enzyme 2 (ACE2) .
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Cat. No.: HY-120833
CAS No.: 219138-21-3
Purity:  99.90%
Target:  

Caspase

Research Areas:  

Others

Ac-Ile-Glu-Thr-Asp-pNA is a substrate for caspase-8. Caspase-8 binds to and cleaves the Ile-Glu-Thr-Asp (IETD) peptide sequence to release p-nitroalinide, which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity .
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Cat. No.: HY-B1751D
CAS No.: 6591-63-5
Quinidine sulfate dihydrate is an orally active antiarrhythmic agent. Quinidine sulfate dihydrate reduces the expression level of P-gp, inhibits P-gp-mediated efflux, increases the intracellular accumulation of P-gp substrates, induces PARP cleavage and Caspase-3 activation, and elevates the proportion of Apoptotic cells at the sub-G1 phase. Quinidine sulfate dihydrate exerts sustained block and open-channel block effects on IK(f). Quinidine sulfate dihydrate alters the urinary metabolic ratio of Amphetamine, modulates the Pentylenetetrazol-induced seizure threshold, and regulates the anticonvulsant effect of Dextromethorphan. Quinidine sulfate dihydrate can be used in studies related to uterine sarcoma and seizures .
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Cat. No.: HY-P3363
Target:  

Caspase

Research Areas:  

Cancer

Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates .
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Cat. No.: HY-P10236
CAS No.: 1135248-58-6
Target:  

Caspase

Research Areas:  

Others

Ac-WEHD-pNA is a colorimetric substrate for caspase 1, 4, 5 and 14, which is utilized to measure the caspase activity .
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Cat. No.: HY-P2616
CAS No.: 189696-01-3
Research Areas:  

Others

Mca-YVADAP-Lys(Dnp)-OH is a fluorogenic substrate for caspase-1 and angiotensin-converting enzyme 2 (ACE2) .
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Cat. No.: HY-W343900
CAS No.: 6912-67-0
Synonyms: DL-Hydroxyproline
Hydroxyproline (DL-Hydroxyproline) is a non-essential amino acid and one of the main components of collagenous tissues. Hydroxyproline acts as a substrate for mitochondrial hydroxyproline oxidase to generate ROS. Hydroxyproline promotes the synthesis of glutathione, DNA, heme and proteins via conversion to Glycine (HY-Y0966). Hydroxyproline promotes the activation of caspase-9 and apoptosis in cancer cells treated with Doxorubicin . Hydroxyproline serves as a biochemical marker. Hydroxyproline is used in research related to various diseases including colon cancer, diabetes and arthritis .
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Cat. No.: HY-P4866
CAS No.: 1361235-89-3
Q-Peptide is an angiopoietin-1 derived peptide (QHREDGS). Q-Peptide interacts with β1-integrin, binds to integrins on the surface of osteoblasts, and serves as an acyl donor substrate for Streptomyces mobaraensis transglutaminase. Q-Peptide activates Akt, MAPKp42/44, ILK, ERK1/2, and downregulates caspase-3/7. Q-Peptide inhibits cell apoptosis, enhances cell adhesion and migration, and promotes osteoblast differentiation, bone matrix deposition and mineralization. Q-Peptide can be used in studies related to myocardial infarction, bone regeneration, diabetic wound repair and human induced pluripotent stem cells .
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Cat. No.: HY-B1751R
CAS No.: 56-54-2
Quinidine (15% dihydroquinidine) (Standard) is the analytical standard of Quinidine (15% dihydroquinidine) (HY-B1751). This product is intended for research and analytical applications. Quinidine (15% dihydroquinidine) is an orally active antiarrhythmic agent. Quinidine (15% dihydroquinidine) reduces the expression level of P-gp, inhibits P-gp-mediated efflux, increases the intracellular accumulation of P-gp substrates, induces PARP cleavage and Caspase-3 activation, and elevates the proportion of Apoptotic cells at the sub-G1 phase. Quinidine (15% dihydroquinidine) exerts sustained block and open-channel block effects on IK(f). Quinidine (15% dihydroquinidine) alters the urinary metabolic ratio of Amphetamine, modulates the Pentylenetetrazol-induced seizure threshold, and regulates the anticonvulsant effect of Dextromethorphan. Quinidine (15% dihydroquinidine) can be used in studies related to uterine sarcoma and seizures .
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Cat. No.: HY-P2615
CAS No.: 210344-94-8
Target:  

Fluorescent Dye

Research Areas:  

Cancer

Ac-VDVAD-AFC is a caspase-specific fluorescent substrate. Ac-VDVAD-AFC can measure caspase-3-like activity and caspase-2 activity and can be used for the research of tumor and cancer .
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Cat. No.: HY-P4403
CAS No.: 223538-61-2
Synonyms: (Z-Asp-Glu-Val-Asp)₂-Rhodamine 110
Research Areas:  

Others

Z-DEVD-R110 ((Z-Asp-Glu-Val-Asp)2-Rhodamine 110) is a fluorogenic caspase-3/7 substrate. Z-DEVD-R110 can be used to detect apoptosis. Z-DEVD-R110 is a rhodamine derivative with two four–amino acid (DEVD) peptides linked to the fuorophore .
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Cat. No.: HY-P10322
Target:  

Fluorescent Dye

Research Areas:  

Cancer

Z-IETD-R110 is a fluorescent substrate of caspases. Z-IETD-R110 acts as a substrate for caspase-8. When caspase-8 is activated, it can recognize and cut Z-IETD-R110, releasing fluorophore, which can be detected by fluorescence microscopy. Z-IETD-R110 can be used to study oxidative stress-induced apoptosis, particularly in pancreatic acinar cells .
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