1. Metabolic Enzyme/Protease
  2. Cytochrome P450
  3. Quinidine sulfate dihydrate

Quinidine sulfate dihydrate 

Cat. No.: HY-B1751D
Handling Instructions

Quinidine sulfate dihydrate is a potent and selective inhibitor of cytochrome P450db and inhibits amphetamine metabolism in vivo. Quinidine sulfate dihydrate enhances the cytotoxicity of vincristine (VCR) in tumor cells and especially in VCR-resistant sublines of P388 leukemia (P388/VCR) and human myelogenous leukemia.

For research use only. We do not sell to patients.

Quinidine sulfate dihydrate Chemical Structure

Quinidine sulfate dihydrate Chemical Structure

CAS No. : 6591-63-5

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Description

Quinidine sulfate dihydrate is a potent and selective inhibitor of cytochrome P450db and inhibits amphetamine metabolism in vivo[1]. Quinidine sulfate dihydrate enhances the cytotoxicity of vincristine (VCR) in tumor cells and especially in VCR-resistant sublines of P388 leukemia (P388/VCR) and human myelogenous leukemia[2].

IC50 & Target

IC50: cytochrome P450db; amphetamine metabolism[1]

Clinical Trial
Molecular Weight

405.50

Formula

C₂₀H₂₄N₂O₂.₁/₂H₂O₄S.H₂O

CAS No.

6591-63-5

SMILES

O=S(O)(O)=O.[H]O[H].C=C[[email protected]]1C[[email protected]](CC[[email protected]]1C2)[[email protected]@]2(C)[[email protected]@H](O)C3=CC=NC4=CC=C(OC)C=C34.[0.5]

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Quinidine sulfate dihydrateCytochrome P450CYPscytochromeP388 leukemiamyelogenousleukemiaInhibitorinhibitorinhibit

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Quinidine sulfate dihydrate
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HY-B1751D
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