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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10355 Results for "
Compound
" in MedChemExpress (MCE) Product Catalog:
Products (10355)
10355 Results for "Compound" in MCE Product Catalog:
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20 Cited Publications
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Fumarate hydratase-IN-1 (compound 2) is a cell-permeable fumarate hydratase inhibitor. Fumarate hydratase-IN-1 has antiproliferative activity against several cancer cell lines with a mean IC50 of 2.2 μM .
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19 Cited Publications
Synonyms: Rheic Acid; Rhubarb yellow; Monorhein
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18 Cited Publications
Synonyms: γ-Secretase-IN-1
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Compound E is a γ-secretase inhibitor. Compound E blocks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC50s of 0.24, 0.37, 0.32 nM, respectively.
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18 Cited Publications
Cat. No.: HY-W015913
CAS No.: 113-24-6
Synonyms: Sodium 2-oxopropanoate; Acetylformic acid sodium
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Ginkgoaceae Plants Monophenols Simple Phenylpropanols Ketones, Aldehydes, Acids Phenols Ginkgo biloba L. Phenylpropanoids Disease Research Fields Cancer
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17 Cited Publications
Synonyms: 8-Methoxypsoralen; Xanthotoxin; 8-MOP
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NG 52 is a potent, cell-permeable, selective, ATP-compatible and orally active Cdc28p and Pho85p kinase inhibitor with IC50s of 7 μM and 2 μM, respectively. NG 52 also inhibits the activity of phosphoglycerate kinase 1 (PGK1) with an IC50 of 2.5 μM. NG 52 is inactive against yeast kinases Kin28p, Srb10, and Cak1p .
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16 Cited Publications
Synonyms: (S)-(+)-[6]Gingerol
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15 Cited Publications
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BMS-986299 (compound 112) is a first-in-class NLRP3 inflammasome agonist with an EC50 of 1.28 μM. (patent WO2018152396A1).
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15 Cited Publications
Cat. No.: HY-N0360
CAS No.: 87205-99-0
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Cardiovascular Disease Quinones Labiatae Samanea saman (Jacq.) Merr. Plants Phenanthrenequinones Disease Research Fields
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14 Cited Publications
Synonyms: 6-Hydroxyapigenin; 4',5,6,7-Tetrahydroxyflavone
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Flavonoids Flavones Labiatae Phenols Polyphenols Plants Disease Research Fields Medicago truncatula Gaertn. Cancer
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Dansylcadaverine (Monodansyl cadaverine) is an autofluorescent compound used for the labeling of autophagic vacuoles. Dansylcadaverine, a high affinity substrate of transglutaminases, can block the receptor-mediated endocytosis of many ligands .
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13 Cited Publications
Synonyms: [6]-Shogaol; 6-Shogaol
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Zingiber officinale Roscoe Monophenols Phenols Plants Disease Research Fields Cancer Zingiberaceae
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13 Cited Publications
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CD38 inhibitor 1 (compound 78c) is a potent CD38 inhibitor with IC50s of 7.3 nM and 1.9 nM for hCD38 and mouse CD38 .
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12 Cited Publications
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Heme Oxygenase-1-IN-1 (Compound 2) hydrochloride is a heme oxygenase 1 (HO-1) inhibitor with an IC50 of 0.25 μM .
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Glutaminase C-IN-1 (Compound 968) is an allosteric inhibitor of Glutaminase C that inhibits cancer cell growth without affecting their normal cellular counterparts .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
