10121-91-2
10121-91-2
Chemical Structure
Dansylcadaverine
Synonym(s): Monodansyl cadaverine
- CAS No.: 10121-91-2
- Formula:C17H25N3O2S
- Molecular Weight:335.46
IUPAC Name: N-(5-aminopentyl)-5-(dimethylamino)naphthalene-1-sulfonamide
InChIKey: MLEBFEHOJICQQS-UHFFFAOYSA-N
SMILES: NCCCCCNS(=O)(C1=CC=CC2=C1C=CC=C2N(C)C)=O
Biological Activity: Dansylcadaverine (Monodansyl cadaverine) is an autofluorescent compound used for the labeling of autophagic vacuoles. Dansylcadaverine, a high affinity substrate of transglutaminases, can block the receptor-mediated endocytosis of many ligands[1][2].
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Dansylcadaverine | 98.80% | Dansylcadaverine (Monodansyl cadaverine) is an autofluorescent compound used for the labeling of autophagic vacuoles. Dansylcadaverine, a high affinity substrate of transglutaminases, can block the receptor-mediated endocytosis of many ligands. | ||||||||||||||||||||
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Dansylcadaverine (solution) | Dansylcadaverine (solution) (Monodansyl cadaverine (solution)) is an autofluorescent compound used for the labeling of autophagic vacuoles. Dansylcadaverine, a high affinity substrate of transglutaminases, can block the receptor-mediated endocytosis of many ligands. Solvent and concentration: DMSO: 10 mM |
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References
- [1]. Huff T, et al. Thymosin beta(4) serves as a glutaminyl substrate of transglutaminase. Labeling with fluorescentdansylcadaverine does not abolish interaction with G-actin. FEBS Lett. 1999 Dec 24;464(1-2):14-20. [Content Brief]
- [2]. Laha D, et al. Interplay between autophagy and apoptosis mediated by copper oxide nanoparticles in human breast cancer cells MCF7. Biochim Biophys Acta. 2014 Jan;1840(1):1-9. [Content Brief]
