1791 Results for "

Compound C

" in MedChemExpress (MCE) Product Catalog:
Products (1791)

1791 Results for "Compound C" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-112914
CAS No.: 468747-17-3
Purity:  98.82%
Target:  

mTOR Autophagy

Research Areas:  

Cancer

mTOR inhibitor-1 (Compound C-4) is an ATP-Competitive mTOR inhibitor which can suppress cells proliferation and inducing autophagy .
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3
3 Cited Publications
Cat. No.: HY-135869
CAS No.: 1254044-38-6
Purity:  99.84%
Research Areas:  

Neurological Disease

Mito-apocynin (C11), an orally active mitochondria-targeted triphenylphosphonium (TPP)-based compound, is synthesized by conjugating the Apocynin moiety with a TPP + cation. Mito-apocynin (C11) selectively targets mitochondria, and shows neuroprotective effect. Mito-apocynin (C11) prevents hyposmia and corrects deficits in motor function .
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3
3 Cited Publications
Cat. No.: HY-126217
CAS No.: 1314796-00-3
Purity:  99.94%
Target:  

Succinate Receptor 1

Research Areas:  

Metabolic Disease

hGPR91 antagonist 1 (Compound 4c) is a potent and selective GPR91 antagonist with an IC50 of 7 nM for human GPR91 .
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3
3 Cited Publications
Cat. No.: HY-N6954
CAS No.: 76996-27-5
Garcinone C, a xanthone derivative, is a natural compound extracted from Garcinia oblongifolia that is used as an anti-inflammatory, astringency and granulation-promoting medicine, and has potential cytotoxic effects on certain cancers. Garcinone C stimulates the expression levels of ATR and 4E-BP1, arrests the cell cycle, inhibits cell viability of the human Nasopharyngeal carcinoma (NPC) cell lines CNE1, CNE2, HK1 and HONE1 in a time‑ and dose‑dependent manner through inhibition of Hedgehog signaling pathway. Garcinone C is orally active .
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3
3 Cited Publications
Cat. No.: HY-N1881
CAS No.: 6665-67-4
4',5-Dihydroxyflavone (Compound 2c; Compound B3) is a type of flavonoid compound. 4',5-Dihydroxyflavone can inhibit various oxidases and its IC50 values for collagenase A (ColA) and α-glucosidase are less than 1 μM and 66 μM respectively; for soybean lipoxygenase-1 (LOX-1), its Ki value is 102.6 μM. 4',5-Dihydroxyflavone can be used in studies on anti-toxicity and anti-diabetes .
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3
3 Cited Publications
Cat. No.: HY-120323
CAS No.: 2101765-81-3
Purity:  98.11%
Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

DRI-C21045 (compound 10) is a potent and selective inhibitor of the CD40-CD40L costimulatory protein-protein interaction (PPI) with an IC50 of 0.17 μM. DRI-C21045 shows concentration-dependent inhibition of the activation of NF-κB and B cell proliferation all induced by CD40L with IC50s of 17.1 μM and 4.5 μM, respectively .
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2
2 Cited Publications
Cat. No.: HY-152229
CAS No.: 1510653-27-6
Purity:  ≥98.0%
Target:  

Liposome

Research Areas:  

Cancer

G0-C14 is a cationic lipid-like compound alkyl-modified polyamidoamine (PAMAM) dendrimer. G0-C14 involves in the preparation of a series of macrophage-targeted nanoparticles (NPs). NPs can be used for agent and vaccine delivery .
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2
2 Cited Publications
Cat. No.: HY-W015913S
CAS No.: 142014-11-7
Synonyms: Sodium 2-oxopropanoate-13C3; Acetylformic acid-13C3 sodium
Sodium 2-oxopropanoate- 13C3 is the 13C-labeled Sodium 2-oxopropanoate. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS .
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2
2 Cited Publications
Cat. No.: HY-Y1213S
CAS No.: 14762-74-4
Carbon- 13C is the 13C labeled Carbon (HY-Y1213). Carbon possesses unique physicochemical properties such as electrical and structural characteristics, making it a core material in the field of fuel cells. Carbon also serves as a pharmaceutical excipient and can be used in the synthesis of other compounds .
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2
2 Cited Publications
Cat. No.: HY-148432
CAS No.: 113143-13-8
Purity:  98.07%
Target:  

HIV

Research Areas:  

Inflammation/Immunology

FGF22-IN-1 (compound c1) is a potent CD4 D1 inhibitor. FGF22-IN-1 can be used as immunosuppressive agent .
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2
2 Cited Publications
Cat. No.: HY-146320
CAS No.: 407587-01-3
Purity:  99.57%
Target:  

Chloride Channel

Research Areas:  

Cancer

ANO1-IN-1 (Compound 9c) is a selective ANO1 channel blocker with an IC50 of 2.56 μM and 15.43 μM against ANO1 and ANO2, respectively. ANO1-IN-1 suppresses strongly proliferation of glioblastoma cells .
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2
2 Cited Publications
Cat. No.: HY-136808
CAS No.: 919010-46-1
Purity:  99.17%
Research Areas:  

Cancer

Pfn1-IN-1 (compound C1) is a Pfn1 inhibitor that inhibits the angiogenic capacity of endothelial cells (EC). Pfn1 is a regulator of the actin cytoskeleton, inducing actin polymerization and essential cellular activities. Pfn1-IN-1 inhibits Pfn1-Actin interaction and Actin polymerization.
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2
2 Cited Publications
Cat. No.: HY-149652
CAS No.: 689270-18-6
Purity:  99.91%
Research Areas:  

Inflammation/Immunology

IRF5-IN-1 (Compound C5) is a conformationally locked inhibitor for SLC15A4. IRF5-IN-1 blocks the downstream IRF5 activation, inhibits the TLR7/8 signaling pathway. IRF5-IN-1 exhibits anti-inflammatory responses .
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2
2 Cited Publications
Cat. No.: HY-122723
CAS No.: 732973-87-4
Purity:  99.45%
Research Areas:  

Cancer

GOT1 inhibitor-1 (compound 2c), a tryptamine-based derivative, acts as a novel, potent and non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC50 of 8.2 uM. GOT1 plays an important role in energy metabolism and Reactive Oxygen Species (ROS) balance. GOT1 inhibitor-1 can be used for the research of pancreatic ductal adenocarcinoma (PDAC) .
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2
2 Cited Publications
Cat. No.: HY-146302
CAS No.: 2770842-10-7
Purity:  99.00%
Research Areas:  

Cancer

14-3-3η Protein inhibitor 1 (Compound C11) is a 14-3-3η protein inhibitor with a KD of 35 µM. 14-3-3η Protein inhibitor 1 shows inhibitory activities against several typical human liver cancer cell lines. 14-3-3η Protein inhibitor 1 induces cell apoptosis and G1-S cell cycle arrest with good metabolic stability .
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1
1 Cited Publications
Cat. No.: HY-131649
CAS No.: 15533-09-2
Purity:  99.32%
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Compound C108 is a G3BP2 inhibitor. Compound C108 also targeted stress granule-associated proteins and Gtpase-activating protein (SH3 domain) binding protein 2. Compound C108 potently inhibits esophageal squamous cell carcinoma (ESCC) cell metastasis .
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1
1 Cited Publications
Cat. No.: HY-128132
CAS No.: 944997-60-8
Purity:  98.16%
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

C3a receptor agonist 1 (compound benzeneacetamide) is a potent C3a receptor agonist. C3a receptor agonist 1 has the potential for the research of acute inflammation .
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1
1 Cited Publications
Cat. No.: HY-134334
CAS No.: 2374285-52-4
Purity:  99.82%
Target:  

DNA/RNA Synthesis

Research Areas:  

Inflammation/Immunology

C/EBPα inducer 1 (compound 78) is a potent inducer of C/EBPα and myeloid differentiation .
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1
1 Cited Publications
Cat. No.: HY-N4123
CAS No.: 164991-86-0
Orcinol gentiobioside (compound 4) is a natural product isolated from the rhizomes of C. breviscapa .
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1
1 Cited Publications
Cat. No.: HY-B1449S10
CAS No.: 159496-16-9
Synonyms: β-Uridine-13C5
Uridine- 13C5 (β-Uridine- 13C5) is a 13C labeled Uridine (HY-B1449). Uridine (β-Uridine) is a nucleoside compound consisting of uracil and a ribose ring, which are linked by a β-N1- glycosyl bond.
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